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Search / Trial NCT06633406

Intelligence and Neurodevelopmental Disorders After Prenatal Exposure to General Anaesthesia

Launched by UNIVERSITAIRE ZIEKENHUIZEN KU LEUVEN · Oct 7, 2024

Trial Information

Current as of July 22, 2025

Enrolling by invitation

Keywords

Anaesthesia Anaesthesia Induced Neurotoxicity Pregnancy

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Prenatal anaesthesia exposure:
  • Inclusion Criteria:
  • Prenatal anaesthesia exposure: Children exposed in utero to maternal general anaesthesia to allow laparoscopy or laparotomy for appendicectomy, adnexal pathology, cholecystectomy or for diagnostic procedures to rule out intra-abdominal pathology
  • No prenatal anaesthesia exposure: Children not exposed to general anaesthesia for non-obstetric or obstetric (e.g. cesarean section) surgery in utero
  • Children born in 2000-2023
  • (Parental) informed consent
  • Exclusion Criteria:
  • Children whose mothers underwent obstetric surgery or foetal surgery/interventions during the same pregnancy.
  • No Dutch-speaking children
  • Diagnosis of severe disability of genetic origin (e.g., Fragil X, Down syndrome,...), history of head trauma, major congenital birth defects

About Universitaire Ziekenhuizen Ku Leuven

Universitaire Ziekenhuizen KU Leuven is a leading academic medical center in Belgium, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. Affiliated with KU Leuven, one of Europe’s premier universities, the institution integrates cutting-edge scientific inquiry with high-quality patient care. It plays a pivotal role in the development and implementation of clinical trials, fostering collaboration between researchers, healthcare professionals, and industry partners to translate scientific discoveries into effective treatments. The hospital's multidisciplinary approach ensures comprehensive patient safety and ethical standards, positioning it as a trusted sponsor in the realm of clinical research.

Locations

Leuven, Vlaams Brabant, Belgium

Bonheiden, Antwerpen, Belgium

Roeselare, West Flanders, Belgium

Patients applied

0 patients applied

Trial Officials

Sarah Devroe, MD, Phd

Principal Investigator

UZ Leuven

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported