Evaluation of an Algae-Based Biphasic Bone Graft Material and Collagen Membrane in the Treatment of Periodontal Intrabony Defects
Launched by CAIRO UNIVERSITY · Oct 8, 2024
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Study population Recruited patients attending the dental clinic at the faculty of dentistry of the University of Cairo, Egypt will be included following the study eligibility criteria.
Population: Patients with periodontal intrabony defects (Stage III and IV periodontitis).
Intervention: Conventional flap with algae-based substitute (AlgOss) combined with collagen membrane.
Control: Conventional flap with collagen membrane.
Outcomes:
Primary outcome:
- Clinical attachment level (CAL)
Secondary outcomes:
* Bleeding on probing (BOP)
* Plaque index (PI)
* Probing pocket depth (PPD)
* G...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. The age is between ≥ 20 to ≤ 65 years old.
- • 2. Presence of intrabony defect
- • 3. Systematically free.
- • 4. The subjects understand the purpose of the study, adhere to the study protocol and given consent to be included in the study.
- • 5. Adequate plaque control and stable periodontal status (full-mouth bleeding score on probing: \<25%, and full- mouth plaque score: \<25%)
- Exclusion Criteria:
- • 1. Smokers
- • 2. Any infection particularly at the intervention site.
- • 3. Teeth mobility more than grade 1.
- • 4. Pregnant or lactating women.
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported