Laparoscopic Versus Open Appendectomy Plus Peritoneal Lavage for Acute Complicated Appendicitis Patients With Diffuse Peritonitis

Launched by SHANGHAI ZHONGSHAN HOSPITAL · Oct 7, 2024

Keywords

ClinConnect Summary

This clinical trial is comparing two types of surgery—laparoscopic (a minimally invasive approach) and open appendectomy (a traditional surgery)—to see which one is more effective and safe for treating patients with acute complicated appendicitis along with diffuse peritonitis, a serious condition caused by an infected appendix. The goal is to determine which method leads to better outcomes for patients who need immediate surgery for this condition.

To be eligible for this trial, participants must be 18 years or older and diagnosed with diffuse peritonitis due to a perforated appendix, which means the appendix has burst and caused infection in the abdominal cavity. Patients will undergo emergency surgery and will have their condition confirmed through tests done during surgery. This trial is currently not recruiting participants yet, but once it starts, eligible individuals will have the opportunity to join and contribute to important research that could improve treatment for this condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged 18 or older;
• • Patients with diffuse peritonitis caused by a perforated appendix confirmed intraoperatively;
• • Patients who underwent emergency appendectomy with peritoneal lavage;
• • Patients who had postoperative pathological confirmation of acute appendicitis.
• • -
• Exclusion Criteria:
• • Patients younger than 18 years;
• • Patients have a history of prior malignancies;
• • Patients with incomplete clinical or pathological records.