Spirometry ,diaphragmatic Ultrasound and Skeletal Muscle Mass in Patients with Chronic Obstructive Pulmonary Disease

Launched by ASSIUT UNIVERSITY · Oct 8, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how well certain tests can help diagnose and understand the severity of Chronic Obstructive Pulmonary Disease (COPD). Specifically, it will use ultrasound to check how well the diaphragm (a muscle that helps with breathing) is working and to measure muscle mass in patients with COPD. The study aims to compare these ultrasound results with traditional breathing tests (called spirometry) to see how they relate to each other.

To participate, you must be a male aged between 40 and 65. There are two groups in this study: one group will include healthy volunteers, while the other group will consist of stable COPD patients who have not had a worsening of their condition in the past six weeks. However, there are certain health conditions that would prevent someone from joining, such as issues that affect breathing or recent surgeries. If selected for the trial, participants will undergo tests that include ultrasound and breathing tests, helping researchers learn more about COPD and how to manage it better in the future.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• * Group A (control group):
• • This group include healthy volunteers who aged ≥ 40 years .
• * Group B (study group):
• • This include stable COPD Patients who will be diagnosed by GOLD 2024 and last excerbation ≥ 6weeks .
• Exclusion Criteria:
• * Group A (control group):
• • Patients with disorders that may affect diaphragmatic function as
• • 1. Musculoskeletal / neurological disorders
• • 2. diaphragmatic eventration \\ hiatus hernia
• • 3. morbid obesity
• • 4. recent thoracic/abdominal surgeries
• • 5. pregnancy; pleurodesis \\fibrothorax.
• • Group B (study group):-
• • Patients need for non- invasive ventilation.
• • Patients with disorders that may affect diaphragmatic function as
• • 1. Musculoskeletal / neurological disorders
• • 2. diaphragmatic eventration \\ hiatus hernia
• • 3. morbid obesity
• • 4. recent thoracic/abdominal surgeries
• • 5. pregnancy; pleurodesis \\fibrothorax