Effect of Dexmedetomidine on Gastric Emptying, Assessed by Ultrasound in Laparoscopic Cholecystectomy

Launched by TANTA UNIVERSITY · Oct 9, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how a medication called dexmedetomidine affects the speed at which food leaves the stomach in patients who are having a laparoscopic cholecystectomy, which is a type of surgery to remove the gallbladder. Researchers will use ultrasound, a painless imaging technique, to measure gastric emptying and see if dexmedetomidine makes a difference.

To participate, you need to be between 21 and 65 years old, and you should be generally healthy (classified as ASA physical status I-II). Unfortunately, if you have certain health issues, like prior stomach surgeries, obesity, or are pregnant, you may not be eligible. If you join the trial, you’ll be monitored closely during your surgery to see how the medication affects your stomach. This study is currently recruiting participants, and it aims to gather important information that could help improve care for patients undergoing this type of surgery in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged 21 to 65 years old.
• • Both sexes.
• • American Society of Anesthesiologists (ASA) physical status I-II.
• • Undergoing elective laparoscopic cholecystectomy surgery
• Exclusion Criteria:
• • Patient's refusal.
• • Patients with abnormalities in gastrointestinal tracts (including previous esophageal or gastric surgery, tumors or stricture).
• • Failure to follow preoperative fasting guidelines.
• • Patients with a body mass index ≥ 35
• • Patients on regular treatment of antacids or prokinetic.
• • Presence of history of disease causing an increase in the incidence of delayed gastric emptying such as: diabetes mellitus, obesity or electrolyte disturbances.
• • Pregnancy.
• • Presence of hepatic or renal dysfunction.
• • Presence of existing condition causing bradycardia such as heart block, or patients on regular calcium channel blockers or beta blockers.