The Efficacy of Repetitive Transcranial Magnetic Stimulation in Patients With Chronic Subjective Tinnitus

Launched by EYE & ENT HOSPITAL OF FUDAN UNIVERSITY · Oct 9, 2024

Keywords

ClinConnect Summary

This clinical trial is looking to find out how effective a treatment called repetitive transcranial magnetic stimulation (rTMS) is for people suffering from chronic subjective tinnitus, which is a persistent ringing or buzzing sound in the ears that doesn’t have an external source. The study will compare two types of rTMS to see which one works better. If you're an adult between 18 and 80 years old and have had tinnitus for at least three months, you might be eligible to participate. Participants will be randomly assigned to receive one of the two treatments.

During the trial, you can expect to receive the rTMS treatment in a clinical setting, where it is non-invasive and does not involve surgery. You will also need to sign a consent form to confirm that you understand what the study involves. It's important to note that certain conditions might exclude you from participating, such as having specific types of hearing loss, a history of seizures or strokes, or having metal implants in your body. If you're interested, this study is currently recruiting participants, so it could be a great opportunity to explore a potential new treatment for tinnitus.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Adults aged between 18 and 80 years old.
• • 2. Experiencing persistant subjective tinnitus for at least 3 months.
• • 3. A score of 38 or more on THI.
• • 4. 50 dB HL or less on the average pure tone threshold (0.5, 1, 2kHz) of the worse ear.
• • 5. Voluntarily participate in the study and sign the informed consent form.
• • 6. Have normal mental status and cognitive function, and be able to cooperate with the research process.
• Exclusion Criteria:
• • 1. Diagnosis of Meniere's disease, conductive hearing loss or objective tinnitus.
• • 2. History of epilepsy or stroke.
• • 3. Diagnosis of acoustic neuroma.
• • 4. Severe sensorineural hearing loss.
• • 5. Surgically or traumatically implanted ferromagnetic foreign bodies, including but not limited to pacemakers, neurostimulators, prosthetic metal heart valves, aneurysm clips (non-titanium alloy), intraocular metal foreign bodies, cochlear implants, metal prostheses, metal joints, fixed steel plates or steel pins.
• • 6. Patients with active metal foreign bodies (metal implants, dentures, contraceptive rings), insulin pumps, etc., who have been evaluated in detail and are at risk for rTMS treatment.
• • 7. Patients taking vestibular sedatives, antipsychotics, anxiolytics, antiepileptics, and ototoxic drugs.
• • 8. Patients with a recent history of alcohol or drug abuse
• • 9. Bell's palsy
• • 10. Acute ear infection within the last 1 month
• • 11. Inability to cooperate or complete the study process
• • 12. Participation in another clinical trial within the last month.
• • 13. Have any condition that may affect compliance or safety
• • 14. Any other condition that, in the opinion of the investigator, makes enrollment in the study inappropriate.