Expand Pulmonary Rehabilitation to Other Chronic Respiratory Diseases Than COPD

Launched by COPENHAGEN UNIVERSITY HOSPITAL, HVIDOVRE · Oct 9, 2024

Keywords

ClinConnect Summary

This clinical trial is looking to expand pulmonary rehabilitation programs—designed to help improve breathing and physical activity—to patients with various chronic respiratory diseases, such as Idiopathic Pulmonary Fibrosis (IPF), Sarcoidosis, Bronchiectasis, and Asthma. The researchers want to see if patients are interested in and can benefit from two types of home-based rehabilitation: structured home-based pulmonary rehabilitation (HPR) and supervised pulmonary tele-rehabilitation (PTR). The goal is to find out if at least 30% of eligible patients are willing to participate, if many of them will stick with the program, and if these rehabilitation methods can improve their breathing, quality of life, and physical function more than standard care.

To join the trial, participants must live in the Capital Region of Copenhagen and have a need for pulmonary rehabilitation, meaning they experience certain breathing difficulties. They should also be able to walk independently and lift light weights. Participants will be randomly assigned to one of three groups: one group will attend supervised exercise sessions twice a week, another will follow a self-initiated program with some professional support, and the third will receive usual care without any exercise intervention. This study is currently recruiting participants, and it's important for anyone interested to know that they need to be able to understand and speak Danish to take part.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Residency in the Capital Region of Copenhagen
• * A clinically assessed need for pulmonary rehabilitation including respiratory symptoms, corresponding to MRC grade 2 or higher and where:
• • 1. Center-based PR is not standard available or
• • 2. Center-based PR being declined by the patient
• • Able to stand up from a chair (height 44-46cm) and walk 10 meters independently (with or without a walking aid)
• • Capable of lifting both arms to horizontal with at least 1 kg dumbbells in each hand
• * And a minimum of one of the below mentioned diagnoses:
• 1. ILD (Interstitial lung disease, Idiopathic pulmonary fibrosis, Sarcoidosis):
• • DLCO lower than 80 % or FVC lower than 80%, HRCT verified, Age higher than 40 years, Confirmed respiratory physician diagnosis
• 2. Asthma:
• • With chronic airway obstruction, ACQ score higher than 1, FEV1 lower than 80%, Age higher than 50 years, Confirmed respiratory physician diagnosis of Asthma
• 3. Bronchiectasis:
• • FEV1 lower than 80%, HRCT verified, Age higher than 40 years, Confirmed respiratory physician diagnosis
• Exclusion Criteria:
• • Cognitive impairment - unable to follow instructions
• • Impaired hearing or vision - unable to see or hear instruction from a tablet
• • Unable to understand and speak Danish
• • Comorbidities where the exercise content is contraindicated