The i4i PRODICT™ Study: Evaluation of the i4i PRODICT™ Test in Different Ethnic Groups (The i4i PRODICT™ Study).

Launched by INSTITUTE OF CANCER RESEARCH, UNITED KINGDOM · Oct 9, 2024

Keywords

ClinConnect Summary

The I4i PRODICT™ Study is a research project aimed at understanding how well the I4i PRODICT™ test works for different ethnic groups in predicting the future risk of prostate cancer. This test uses a simple saliva sample to look for common and rare genetic changes that may indicate a person's likelihood of developing prostate cancer. The study is particularly focused on men aged 40 to 55 who identify as Black African/Black African-Caribbean, White European, South Asian, or East Asian, and have no history of prostate cancer.

If you meet these criteria and decide to participate, you will undergo the saliva test and provide information to help researchers learn more about how acceptable and useful this test is for different communities. It's important to note that the study is not currently recruiting participants, but when it does, it will exclude anyone who has had a prior diagnosis of prostate cancer, those with mixed ancestry, and individuals facing significant psychological challenges. This study aims to gather important information that could help in the future prevention and early detection of prostate cancer in various ethnic groups.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • People with a prostate\* (PwP). \*People with a prostate is defined as people born with male reproductive organs.
• • Aged 40 to 55 years.
• • People of either (i) Black African/Black African-Caribbean; (ii) White European; or (iii) South Asian or East Asian ancestry. These are defined as individuals with 4 grandparents of the same ancestry.
• • Absence of any psychological, familial, sociological or geographical situation potentially hampering compliance with the study protocol and follow-up schedule.
• Exclusion Criteria:
• • Previous diagnosis of prostate cancer.
• • People of mixed ancestry
• • Previous diagnosis of cancer with a life-expectancy of less than five years.
• • Negative prostate biopsy within one year before recruitment.
• • Any significant psychological conditions that may be worsened or exacerbated by participation in the study.