Postoperative Basal Bolus or Sliding Scale Insulin Regimen in DM2 and Its Effect on Surgical Site Infections.

Launched by ABRAHAM HULST, MD, PHD · Oct 10, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how different types of insulin treatment can affect the chance of getting infections after surgery in adults with type 2 diabetes. Specifically, it compares two methods: a "basal bolus" insulin regimen, which provides a steady supply of insulin, versus a "sliding scale" insulin regimen, which adjusts insulin based on blood sugar levels. The study aims to see if using the basal bolus method can help lower the risk of surgical site infections within the first 30 days after surgery.

To participate in this trial, you need to be at least 18 years old, have type 2 diabetes, and be scheduled for gastrointestinal or vascular surgery that requires at least one night in the hospital. If you are interested, you will be asked for your consent to take part. The trial is currently recruiting participants of all genders. It’s important to know that certain individuals, like those with type 1 diabetes or those undergoing specific types of surgery, may not be eligible to join. If you take part, you will receive either the basal bolus or sliding scale insulin treatment while your progress is monitored during your hospital stay.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged 18 or older
• • Diagnosed with type 2 diabetes mellitus
• • Undergoing gastointestinal or vascular surgery
• • Admitted to one of the participating surgical wards
• • Expected duration of stay at least one overnight stay
• • Willing and able to provide informed consent
• Exclusion Criteria:
• • Diagnosed with type 1 diabetes mellitus
• • Female of child-bearing potential who is pregnant or breastfeeding.
• • Undergoing complete pancreatectomy
• • Undergoing bariatric surgery
• • Patients using a continuous insulin pump at home
• • Patients undergoing a necrotectomy/wound debridement from a pre-existent wound.