Microbiota Profiles in Newly Married Couples: Potential Effects on Vision, Sleep and Psychometric Parameters
Launched by REZA RASTMANESH · Oct 10, 2024
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
The metabolic activity, diversity and composition of the gut microbiota vary significantly between healthy individuals and insomniacs, and also between hypersomniacs and healthy people. While Clostridiales and Bacteroides are regarded to be the two most important biomarkers for differentiating between healthy people and insomniacs, a recent study demonstrated that an enhanced relative abundance of five genera including Lachnospiraceae UCG010, Hungatella, Collinsella, Gordonibacter and Blautia may be correlated with a diminished risk of some types of hypersomnia (narcolepsy type one). Contra...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Sleep disorder (insomnia and hypersomnia)
- • Depressive/anxiety states
- Exclusion Criteria:
- • Medicines known to affect gut/oral/ocular microbiota composition
- • Pregnant/pregnancy
- • Divorce during the study
- • Antibiotics use in the past month
- • Ongoing, active ocular infection, including conjunctivitis.
- • Not having any prior history with Dry eye disease
About Reza Rastmanesh
Reza Rastmanesh is a distinguished clinical trial sponsor known for his commitment to advancing medical research and innovation. With a strong background in clinical pharmacology and a focus on developing novel therapeutic solutions, he leads initiatives that emphasize rigorous scientific methodology and ethical standards. His work is characterized by collaboration with healthcare professionals and institutions to ensure that clinical trials are conducted efficiently and effectively, ultimately aiming to enhance patient outcomes and contribute to the body of medical knowledge. Through his leadership, Reza Rastmanesh is dedicated to fostering an environment of excellence in clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Tehran, , Iran, Islamic Republic Of
Patients applied
Trial Officials
Reza Rastmanesh Principal investigator, unaffilaited, PhD
Principal Investigator
Abolfazl Sadeghinejad, MD
Study Director
Javid Azizi, MD
Study Director
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported