Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau

Launched by UNIVERSITY OF CHICAGO · Oct 11, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to manage pain after knee surgery for people who have a specific type of broken bone called a tibial plateau fracture. Currently, doctors use a standard method where they inject numbing medication near the surgical site to help with pain. This study aims to see if injecting numbing medication into a nerve that controls pain in a larger area of the knee (known as a nerve block) can provide better pain relief after surgery.

To be eligible for this trial, participants need to be adults aged 18 or older who are having surgery to fix an acute tibial plateau fracture. However, some people may not qualify for various reasons, such as having certain other medical conditions or previous treatments that could affect their results. If you participate, you can expect to receive either the standard pain management or the nerve block treatment, and the researchers will monitor your pain levels after your surgery to see which method works better.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • • Any adult patient (ages 18 and over) undergoing open reduction internal fixation of an acute isolated tibial plateau fracture
• Exclusion Criteria:
• • Subjects younger than 18
• • Polytraumatized Subjects
• • Subjects with pathologic fractures
• • Subjects with tibial plateau fractures treated nonoperatively
• • Subjects with tibial plateau fractures treated operatively but with re-operations at the same site
• • Subjects with open fractures
• • Subjects with fracture-dislocations
• • Subjects with active or history of anxiety
• • Subjects with visual analog scale anxiety score ≥ 7 measured preoperatively
• • Subjects with chronic pain syndromes
• • Subjects with chronic opioid use
• • Subjects with illicit drug use disorder
• • Subjects with alcohol abuse disorder
• • Subjects with kidney disease precluding use of ketorolac
• • Subjects with liver disease precluding the use of acetaminophen
• • Subjects with allergy to acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs), opiates or local anesthesia
• • Subjects with inability to provide a visual analog scale score postoperatively
• • Subjects with contraindications to receiving peripheral nerve blocks, including relevant neurologic deficits, active infection at sites of injections - re-operation at the same site