Psyllium in Pediatric IBS

Launched by DR BRUNO CHUMPITAZI, M.D. · Oct 10, 2024

Keywords

ClinConnect Summary

This clinical trial is studying whether a type of fiber called psyllium can help children with irritable bowel syndrome (IBS) feel better when they eat foods containing fructans, which are a type of sugar. The researchers want to see how psyllium affects the bacteria in the gut and if it can reduce the stomach issues that some kids experience after eating fructans. Participants will first follow a special diet for six days to see if fructans make their IBS symptoms worse. If they do, they can join the second part of the study, which involves two weeks of testing where they will eat a specific diet with fructans along with either psyllium or glucose.

To be eligible for this trial, children aged 12 to 17 must meet certain criteria for IBS. They should not have had previous bowel surgery or serious gastrointestinal disorders, nor should they have other chronic health issues. Additionally, they must not have taken antibiotics or probiotics in the last three months. During the trial, participants will keep track of their pain and bowel movements, provide stool samples, and undergo some tests to measure gut acid levels. This study is currently looking for participants, and it's a chance for kids with IBS to potentially find relief from their symptoms.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Children between the ages of 12-17 years meeting pediatric Rome IV criteria for IBS
• Exclusion Criteria:
• • Children who have had previous bowel surgery, have documented GI disorders (e.g., ulcerative colitis), or a serious chronic medical condition (e.g., diabetes)
• • weight and/or height are \> or \< 2 SD for age
• • have chronic conditions with GI symptoms (e.g., cystic fibrosis)
• • have been on antibiotics or probiotics within 3 months (because of potential alterations to the GI microbiome0
• • girls who are pregnant (tested with urine beta-human chorionic gonadotropin at the initial visit)