Cardiovascular Ultrasound for the Rehabilitation of Patients With Coronary Heart Disease After PCI

Launched by QILU HOSPITAL OF SHANDONG UNIVERSITY · Oct 10, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring whether cardiovascular ultrasound therapy can help patients with coronary heart disease recover better after a procedure called PCI, which stands for percutaneous coronary intervention. The researchers want to find out if this therapy improves heart function and overall health, while also checking for any potential side effects. Participants in the study will either receive the ultrasound treatment or a placebo (which is a fake treatment that doesn't have any active ingredients) for 20 minutes, twice a day, over ten days, starting one day after their PCI. They will be monitored at different times to see how their heart and overall health are responding.

To join this trial, participants need to be at least 18 years old and diagnosed with coronary artery disease that requires elective PCI. They should not have had any major complications during the PCI procedure and must meet certain health criteria, like having normal heart enzyme levels. Throughout the study, participants will keep track of their symptoms and complete assessments related to their mental health, including feelings of depression and anxiety. This trial is a great opportunity for eligible patients to potentially benefit from a new type of therapy while contributing to important medical research.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria
• • 1. Age of enrollment at least 18 years 2. Patients with confirmed coronary artery disease requiring elective PCI 3. TIMI flow grade 2 or above after PCI 4. No intraoperative complications of PCI such as entrapment, reflux, or perforation of coronary artery.
• • 5. The skin in the anterior chest area is intact and not broken. 6. Cardiac enzymes and troponin I are within normal range before enrollment. Exclusion Criteria
• • 1. Patients with ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction.
• • 2. Occlusion of branch vessels during PCI.
• • 3. Patients with perioperative use of hormones or immunosuppressants
• • 4. Combined infection or other inflammatory diseases
• • 5. Postoperative fever
• • 6. Patients are allergic to contrast media or cardiovascular ultrasound acoustic head-related materials.
• • 7. Changes in lipid-lowering, antiplatelet, and antihypertensive drug regimens during treatment.
• • 8. Patients with a clear diagnosis of autoimmune disease
• • 9. Patients who have undergone other surgeries in the past 7 days or have a history of trauma.
• • 10. Patients infected with novel coronavirus in the past month.
• • 11. Previous PCI treatment
• • 12. Previous cardiovascular ultrasound treatment
• • 13. Diabetic patients