A Prospective Observational Study of Transcranial Doppler Ultrasound in the Assessment of Cerebral Blood Flow After Polyetheretherketone Cranioplasty

Launched by RENJI HOSPITAL · Oct 13, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how well a special type of ultrasound, called transcranial Doppler ultrasound, can be used to check blood flow in the brain after a specific surgery known as cranioplasty, which involves using a material called polyetheretherketone (PEEK) to repair skull defects. Researchers will measure blood flow in different arteries of the brain both before and 10 days after the surgery to see how the procedure affects cerebral blood flow. This study is important because it aims to improve our understanding of how the brain responds to this type of surgery.

To participate in this trial, you need to be at least 18 years old and scheduled for PEEK cranioplasty surgery. You should also have a cranial bone defect that allows access for the ultrasound. If you have a complete cranial bone in the area where the ultrasound will be done, you won't be eligible. If you join the study, you will undergo the ultrasound before your surgery and again 10 days after. The information gathered will help doctors learn more about brain health and recovery following this type of surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age of 18 years or older;
• • 2. Proposed polyetheretherketone cranioplasty;
• • 3. Incomplete cranial bone in the lateral temporal window;
• • 4. Signed informed consent for surgery and informed consent for research.
• Exclusion Criteria:
• • 1)Although cranioplasty is proposed, the cranial bone in the temporal region is intact.