STarting incrEmental Prescription of Peritoneal Dialysis

Launched by THE UNIVERSITY OF QUEENSLAND · Oct 13, 2024

Keywords

ClinConnect Summary

The STEP-PD trial is a research study looking at how to start patients on peritoneal dialysis (PD) in a safer and more effective way. PD is a treatment for kidney failure that allows patients to do dialysis at home, giving them more flexibility in their daily lives. Currently, many patients are prescribed PD for a full 24 hours a day, every day, which may not be necessary and could even be harmful. This trial will explore whether starting with a lower dose of PD and gradually increasing it over time is a better approach.

To participate in this trial, you need to be an adult (18 years or older) who is starting PD as your first type of dialysis and has been on dialysis for less than a month. You should also be able to understand and agree to take part in the study. However, if you have very low urine output, have had a kidney transplant before, are not expected to stay on dialysis for at least a year, or are pregnant or planning to become pregnant during the trial, you won’t be eligible. If you join the study, you can expect close monitoring and support as researchers assess the best way to start PD treatment for patients like you.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • adults (≥18 years) commencing PD as their first dialysis therapy (and been on dialysis for \<1 month)
• • able to give informed consent
• Exclusion Criteria:
• • urine output \<0.5L/day
• • previous kidney transplant
• • unlikely to be on dialysis for ≥1 year.
• • known or planned pregnancy during the trial