AI-based Skeleton Recognition System for Rehabilitation Exercise in Breast Cancer Survivors: A Randomized Controlled Trial

Launched by FUDAN UNIVERSITY · Oct 14, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new technology that uses artificial intelligence (AI) to help breast cancer survivors who are experiencing muscle and joint pain due to a type of hormone therapy called aromatase inhibitors. The aim is to create a special program that supports patients in doing rehabilitation exercises at home, making it easier for them to stay active and improve their quality of life. By using AI, the system will be able to provide real-time feedback during exercises, ensuring that participants engage in appropriate movements tailored to their needs.

To be eligible for the trial, participants must have been diagnosed with hormone receptor-positive breast cancer and be currently receiving aromatase inhibitors. They should also be postmenopausal and experiencing some level of bone or joint pain. Importantly, those interested in joining the study should not be involved in other physical therapy or exercise programs that could interfere with the trial. Participants will have the opportunity to engage in a personalized exercise regimen that may help alleviate their symptoms while being monitored and supported by the AI system. This innovative approach aims to make rehabilitation more accessible and effective for breast cancer survivors.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Pathologically confirmed hormone receptor-positive breast cancer (stage I, II, III).
• • 2. Initiation of treatment with aromatase inhibitors (e.g., anastrozole, letrozole, exemestane).
• • 3. Postmenopausal women, including those with surgically induced menopause. 4. Clear consciousness, no cognitive or communication impairments, and able to comply with the intervention.
• • 5. Informed consent obtained, with voluntary participation in the study. 6. Bone and joint symptoms with a Brief Pain Inventory (BPI) score of ≥3, or presence of at least one of the following risk factors: elevated bone turnover markers, reduced vitamin D levels, increased inflammatory cytokines, elevated C-reactive protein, or elevated rheumatoid factor.
• • 7. Not participating in any physical therapy or exercise-based interventions that may interfere with this study.
• Exclusion Criteria:
• • - 1. Recurrence of breast cancer or distant metastasis. 2. Presence of other malignancies. 3. Diagnosed rheumatoid arthritis, bone and joint trauma, or other severe bone and joint diseases.
• • 4. Bone mineral density T-score \<-2.5. 5. Presence of absolute contraindications to exercise.