Effect of Targeted Endodontic Microsurgery on Quality of Life and Healing on Mandibular Molars

Launched by POSTGRADUATE INSTITUTE OF DENTAL SCIENCES ROHTAK · Oct 13, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a specialized dental surgery called targeted endodontic microsurgery. This procedure aims to treat persistent dental problems at the tips of the roots of mandibular molars (the large teeth at the back of your mouth) after traditional root canal treatments haven't worked. The surgery uses advanced techniques and tools to carefully remove infected tissue and other issues when regular treatments are not an option. It also includes the use of 3D-printed guides to help the dentist perform the surgery with greater accuracy, potentially leading to better healing and fewer complications.

To participate in this trial, you must be between 18 and 55 years old and generally healthy, meaning you don’t have serious medical issues that could complicate surgery. You should also have a specific type of dental problem (a periapical lesion) that hasn’t improved with standard treatments, and your tooth should be otherwise healthy. If you’re selected, you can expect a thorough evaluation and to be part of a study that may offer new hope for treating difficult dental conditions. Please note that people with certain dental issues or health conditions, like pregnancy or specific mental health disorders, may not be eligible to join.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients between 18-55 years of age
• • No general medical contraindications for oral surgical procedures (ASA-1 according to the classification of the American Society of Anesthesiologists)
• • ASA 1- A normal healthy patient. Example: Fit, non-obese (BMI under 30), a nonsmoking patient with good exercise tolerance.
• • Tooth with a peri-radicular lesion of strictly endodontic origin (Symptomatic and Asymptomatic apical periodontitis) with the size of lesion 5mm≤10mm and intact cortical bony plate in CBCT
• • Tooth with non-surgical retreatment unfeasible or previously failed (post, anatomy, or iatrogenic complications like irrepairable ledges, separated instruments and apical transportation) Tooth with adequate final restoration without clinical evidence of coronal leakage but with persisting periodontal lesion.
• • No spontaneous pain or swelling
• • Periodontically healthy teeth at tooth level.
• Exclusion Criteria:
• • Presence of vertical root fracture
• • Presence of root perforations
• • Miller class III/IV mobility
• • Presence of root resorption
• • Combined Endodontic-Periodontic lesions
• • Pregnancy
• • Patients with neuropsychiatric disorders and other systemic conditions
• • Smokers.