Normal Chinese Lifespan Brain Charts Initiative (NCLBCI)

Launched by BEIJING TIANTAN HOSPITAL · Oct 14, 2024

Keywords

ClinConnect Summary

The Normal Chinese Lifespan Brain Charts Initiative (NCLBCI) is a research study that aims to gather brain imaging data from over 10,000 participants of various ages. This study focuses on understanding how major brain diseases, like Multiple Sclerosis, Alzheimer’s disease, and stroke-related conditions, affect brain structure and function over time. By using advanced imaging techniques, researchers will create reference charts that show what healthy brain scans look like at different ages. These charts will help doctors diagnose brain diseases earlier and tailor treatments to individual patients based on their specific brain health.

To participate in the study, individuals should be generally healthy, able to lie still during the imaging process, and not have any metal implants in their bodies, as these could interfere with the scans. Participants can expect to undergo non-invasive brain scans, which are painless and do not involve any surgery. The results will contribute to a better understanding of brain health in the Chinese population, and the findings will be accessible online, allowing users to see how their brain health compares to established norms. This research has the potential to significantly improve how brain diseases are diagnosed and treated.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Healthy individuals with normal physical function who can lie supine without medical issues (e.g., no difficulty breathing, physical pain, nausea, or dizziness);
• • 2. No claustrophobia;
• • 3. No metal implants in the body (e.g., metal teeth, intrauterine devices, pacemakers, etc.).
• Exclusion Criteria:
• • 1. Presence of metal implants in the body;
• • 2. Individuals who have undergone aneurysm surgery or have aneurysm clips in the brain;
• • 3. Contraindications to MRI examination;
• • 4. Prospective cohort participants who are unable to meet follow-up requirements.