The Effect of Short-term Bed Rest on Cardiac Function Measured by Cardiac Magnetic Resonance Imaging

Launched by UNIVERSITY OF COPENHAGEN · Oct 14, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating how short periods of bed rest, specifically 4 hours, might affect heart function in healthy individuals. Researchers will use a specialized imaging technique called cardiac magnetic resonance imaging (CMR) to measure how the heart performs before and after the bed rest. The goal is to see if lying down for a short time changes how well the heart pumps blood.

To participate in this study, you need to be between 18 and 80 years old and in good health, meaning you shouldn't be taking any medications that affect heart function or have certain medical conditions like diabetes or kidney disease. If you join, you will lie in bed for three hours while researchers take repeated heart images to assess any changes. It’s important to note that you should be open to learning about any health information that may come up during the CMR scans. This study, which will start recruiting participants soon, aims to provide valuable insights into heart function and the reliability of these imaging tests over short timeframes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male or female.
• • Age between 18-80 years old.
• • No use of medications with influence on heart function.
• • For ethical reasons, we only include participants who are willing to be informed on new health information, as CMR may reveal relevant secondary health findings.
• Exclusion Criteria:
• • Diabetes, kidney, or liver disease.
• • Contraindications to CMR, e.g., abdominal height exceed limitations of the MR-scanner, pacemaker, aortastent, neurostimulator, or other electronic device implanted, implanted metal devices, severe claustrophobia, or physiological diseases.
• • Pregnant, lactating, or planning to become pregnant within the study period.
• • In ongoing cancer treatment.
• • Blood donation during and \< 1 month prior to study.
• • Simultaneous participation in other clinical trials potentially affecting the study outcome.
• • Inability, physically or mentally, to comply with the procedure required by the study protocol ad evaluated by the primary investigator, study manager or clinical responsible.