TMS with Real-time E-field and EEG Source Imaging

Launched by BRIGHAM AND WOMEN'S HOSPITAL · Oct 15, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a method to improve how we target and stimulate specific areas of the brain using a technique called transcranial magnetic stimulation (TMS). The goal is to understand how different regions of the brain communicate with each other, particularly in a network that helps with tasks requiring attention and decision-making. Healthy volunteers aged 18 to 64 who meet certain health criteria, such as not having any neurological disorders or metal implants, may be eligible to participate.

Participants will have two visits. During the first visit, they will undergo an MRI scan to gather important information about their brain. In the second visit, they will experience four different TMS sessions while completing a computer-based task. Researchers will collect data to see if stimulating targeted areas of the brain can help improve how quickly and accurately participants respond during the task. This study is not yet recruiting, but it aims to advance our understanding of brain function in healthy individuals.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age greater than 18 and less than 65 years.
• • 2. Able to understand and give informed consent/assent.
• • 3. No prior neuropsychiatric, neurological disorders, epilepsy, or seizures.
• • 4. No metal implants.
• • 5. Absent of lesions or tumors from MRI scans.
• Exclusion Criteria:
• • 1. The presence of a cardiac pacemaker or pacemaker wires.
• • 2. Metallic particles in the eye.
• • 3. Vascular clips in the head or previous neurosurgery.
• • 4. Prosthetic heart valves.
• • 5. Significant claustrophobia.
• • 6. Non-fixed metallic particles (shrapnel).
• • 7. Any magnetic metallic particles in the body.
• • 8. Failure to assure non-pregnant status.
• • 9. Failure to perform the task of lying still.