Clinical Classification and Imaging Markers in Patients of Obesity
Launched by THE AFFILIATED NANJING DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL · Oct 17, 2024
Trial Information
Current as of August 20, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
In this project, individuals with obesity and control individuals were recruited and followed up every year. Clinical neuropsychological scores, olfactory function tests, and functional magnetic resonance imaging (fmri) were performed to describe the brain function characteristics under different odor stimulation in fasting and after eating, and to explore the pathogenesis and clinical classification of obese patients. The correlation analysis between imaging analysis values and clinical laboratory data, neuropsychological scores and olfactory behavior scores was performed to explore indica...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients with BMI≥28kg/m2
- • Aged 18-65 years of both sexes, right-handed
- • At least 6 years of education
- • Patients agreed and signed the informed consent
- Exclusion Criteria:
- • Fewer than 6 years of education
- • Left-handedness
- • Dementia
- • Acute metabolic complications such as diabetic ketoacidosis
- • Hyperglycaemic hyperosmolar state and hypoglycaemic coma within the previous 3 months; history or presence of neurological or psychiatric disorders;
- • Presence of hypothyroidism;
- • History of malignancy, or severe kidney or liver dysfunction.
About The Affiliated Nanjing Drum Tower Hospital Of Nanjing University Medical School
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School is a leading academic medical institution in China, renowned for its commitment to advanced healthcare, research, and medical education. As a prominent sponsor of clinical trials, the hospital leverages its state-of-the-art facilities and multidisciplinary expertise to facilitate innovative medical research aimed at improving patient outcomes. With a focus on translational medicine, the institution fosters collaborations between clinicians and researchers to accelerate the development of novel therapies and enhance the understanding of complex diseases. Through its rigorous adherence to ethical standards and regulatory compliance, the hospital is dedicated to advancing medical knowledge and contributing to the global scientific community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Nanjing, Jiangsu, China
Patients applied
Trial Officials
Yan Bi, M.D., Ph.D.
Study Director
Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported