Comparison of the Clinical Efficacy and Safety of Endoscopic Superior Rectal Mucosal Ligation and Hemorrhoids Ligation

Launched by THE AFFILIATED HOSPITAL OF QINGDAO UNIVERSITY · Oct 17, 2024

Keywords

ClinConnect Summary

This clinical trial is comparing two different methods for treating internal hemorrhoids, specifically endoscopic superior rectal mucosal ligation and hemorrhoids ligation. Both treatments aim to relieve the symptoms of hemorrhoids, which can be uncomfortable and painful. The study will look at how effective and safe each method is for patients. To participate, individuals need to be diagnosed with grade II-III internal hemorrhoids according to specific guidelines and must agree to take part by signing a consent form.

Participants in the study will undergo a routine endoscopic procedure, which is a way for doctors to see inside the rectum using a thin tube with a camera. After the procedure, there will be follow-up surveys to monitor recovery and outcomes. However, some people may not be eligible, such as those with serious heart, liver, or kidney diseases, or those who have had certain treatments or conditions that could complicate the procedure. This trial is not yet recruiting participants, but it will be open to adults aged 65 and older, regardless of gender.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. According to the Goligher classification in the Chinese guidelines for the diagnosis and treatment of hemorrhoids (2020) , patients who are diagnosed with grade II-III internal hemorrhoids .
• • 2. Patients who voluntarily participate and sign the informed consent form.
• Exclusion Criteria:
• • 1. patients who had severe heart, liver, and kidney disease.
• • 2. patients who had severe immune deficiency.
• • 3. patient\'s general condition is too poor to tolerate endoscopic therapy.
• • 4. patients had a history of pelvic chemoradiotherapy.
• • 5. patients had severe infection or inflammatory lesion in the rectum or anal canal,or the rectum or anal canal had undergone surgery.
• • 6. patient is a pregnant woman.
• • 7. patients who disagree with endoscopic treatment and are concerned about the possible risks refused to sign the informed consent form.
• • 8. the follow-up time is insufficient and the clinical data were incomplete.