China Diabetes Cognitive Dysfunction Early Diagnosis and Intervention Study (China-DECODE Study)

Launched by THE AFFILIATED NANJING DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL · Oct 18, 2024

Keywords

ClinConnect Summary

The China Diabetes Cognitive Dysfunction Early Diagnosis and Intervention Study, also known as the China-DECODE Study, is focused on understanding how type 2 diabetes can lead to problems with thinking and memory, including conditions like mild cognitive impairment and dementia. Researchers want to find ways to detect these issues early and improve treatment options, as cognitive problems can significantly impact the lives of people with diabetes, especially older adults. The study aims to create a well-organized system for collecting information and biological samples from participants, which will help in developing better diagnostic tools and treatment strategies.

To participate in this study, you need to be at least 45 years old and have been diagnosed with type 2 diabetes. You must also be willing to complete some tests that assess your thinking abilities. However, if you have had any serious complications from diabetes recently, have certain neurological or psychiatric conditions, or have other specific health issues, you may not be eligible. Participants can expect to undergo detailed assessments and contribute to important research that could lead to better care for people with diabetes and cognitive difficulties in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥45 years;
• • Type 2 diabetes diagnosed according to the American Diabetes Association criteria;
• • Willingness and ability to complete systematic neuropsychological tests;
• • Understanding of the research procedures and methods, potential benefits and risks of the trial, and sign written informed consent.
• Exclusion Criteria:
• • Fewer than 6 years of education;
• • Left-handedness;
• • Dementia;
• • Acute metabolic complications such as diabetic ketoacidosis, hyperglycaemic hyperosmolar state and hypoglycaemic coma within the previous 3 months;
• • History or presence of neurological or psychiatric disorders;
• • Presence of hypothyroidism;
• • History of malignancy, or severe kidney or liver dysfunction.