Effectiveness of Topical Vancomycin in Reducing Sternal Wound Infections Post-Cardiac Surgery

Launched by LIAQUAT NATIONAL HOSPITAL & MEDICAL COLLEGE · Oct 18, 2024

Keywords

ClinConnect Summary

This clinical trial is studying whether applying vancomycin powder directly to the chest wound after heart surgery can help prevent infections. Sternal wound infections can lead to serious problems and longer hospital stays, so researchers want to see if this treatment can improve recovery. The study will involve 24 adult patients who are having various types of heart surgeries, and they will be divided into two groups: one will receive standard care, while the other will get the vancomycin powder on their wound.

To participate in the trial, patients need to be between 21 and 80 years old and undergoing specific heart surgeries. However, those who have allergies to vancomycin or are having repeat surgeries will not be eligible. Participants can expect to have their wounds checked at three different times after surgery to see how well the treatment works. This trial has not started recruiting participants yet, but it aims to find a better way to prevent infections after heart surgery, which could lead to quicker recoveries and less time in the hospital.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • .Patients aged between 21 and 80 years were included in the study.
• • Both male and female participants were eligible.
• • Patients undergoing various adult cardiac surgical procedures, including coronary artery bypass grafting (CABG), atrial septal defect (ASD) repair, ventricular septal defect (VSD) repair, and valve replacement, were considered for inclusion.
• Exclusion Criteria:
• • Patients who did not provide informed consent were excluded from the study.
• • Individuals with a known sensitivity to vancomycin were not eligible.
• • Pediatric patients were excluded.
• • Patients undergoing redo surgeries were also excluded from participation