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Search / Trial NCT06651658

Oxford Pleural Embolisation Trial

Launched by OXFORD UNIVERSITY HOSPITALS NHS TRUST · Oct 18, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Lung Cancer Lung Metastases Lung Ablation Pleural Embolisation Pleural Blood Patch

ClinConnect Summary

The Oxford Pleural Embolisation Trial is studying a new technique called the pleural blood patch (PBP) to see if it can help reduce complications for patients undergoing thermal ablation for lung cancer. Thermal ablation is a treatment that uses heat to destroy lung tumors, but it can sometimes cause air leaks from the lungs, leading to the need for a drainage tube. This trial will compare two groups of patients: those who receive lung ablation with the PBP technique and those who do not. The researchers hope to find out if using PBP can lower the number of patients who need a drain, as well as improve recovery times and reduce hospital stays.

To participate in the trial, you must be 18 years or older and clinically indicated for lung ablation. However, if you have three or more lung lesions that need treatment at the same time, or if you cannot proceed with the lung ablation procedure, you may not be eligible. If you join the study, you can expect to be randomly assigned to one of the two treatment groups and will be monitored for various outcomes, such as the amount of air leakage and your overall recovery experience. This trial is important because it may help make lung cancer treatments safer and quicker, potentially allowing patients to go home the same day as their procedure.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Clinically indicated for lung ablation.
  • Willing and capable of giving informed consent.
  • Aged 18 years or above.
  • Exclusion Criteria:
  • Unable to proceed to lung ablation procedure.
  • 3 or more lung lesions to be ablated in the same setting.

About Oxford University Hospitals Nhs Trust

Oxford University Hospitals NHS Trust is a leading healthcare provider in the UK, renowned for its commitment to clinical excellence, research, and innovation. As a prominent academic health organization, it integrates cutting-edge medical research with patient care, facilitating a wide range of clinical trials across various therapeutic areas. The Trust collaborates closely with the University of Oxford, leveraging its world-class expertise to advance medical knowledge and improve treatment options. With a focus on patient safety and ethical standards, Oxford University Hospitals NHS Trust is dedicated to contributing to the development of new therapies and enhancing health outcomes through rigorous scientific inquiry.

Locations

Oxford, , United Kingdom

Patients applied

0 patients applied

Trial Officials

Dr Yan-Lin Li Consultant Interventional Radiologist, EBIR FRCR FHKAM

Principal Investigator

Oxford University Hospitals NHS Foundation Trust/ University of Oxford

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported