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Search / Trial NCT06653933

Study of Sleep Quality in the Intensive Care Unit and Association with Weaning from Invasive Ventilation in Patients with Chronic Obstructive Bronchopneumopathy.

Launched by UNIVERSITY HOSPITAL, GRENOBLE · Oct 21, 2024

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

Copd Sleep Quality Weaning Of Mechanical Ventilation

ClinConnect Summary

This clinical trial is studying how sleep quality affects the ability of patients with Chronic Obstructive Pulmonary Disease (COPD) to be weaned off invasive mechanical ventilation in the Intensive Care Unit (ICU). When patients are on a ventilator, they often experience sleep disturbances, which can make it harder for them to breathe on their own again. The researchers want to compare the sleep patterns of COPD patients who successfully transition off the ventilator with those who do not. They believe that poor sleep in the days leading up to the weaning test might be a reason for failure.

To be eligible for this study, patients must be diagnosed with COPD, have been on a ventilator for more than 24 hours, and be able to respond adequately when evaluated. Patients who have certain brain or muscle conditions, are pregnant, or do not want to participate will not be included. If you or a loved one is considering participation, the study will involve monitoring sleep patterns and assessing how they relate to the weaning process from the ventilator. This could help improve care for future ICU patients with COPD.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients diagnosed with COPD according to the GOLD criteria.
  • Mechanical ventilation by endotracheal tube and mechanical ventilation for \> 24 hours.
  • Withdrawal of treatment with continuous sedation and/or neuroleptics.
  • Adequate recovery with Glasgow Coma Scale ≥ 8.
  • Exclusion Criteria:
  • Patients with central nervous system damage or neuromuscular pathology.
  • Pregnant or postpartum patients.
  • Patients or their relatives who object to participating in the study.

About University Hospital, Grenoble

The University Hospital of Grenoble is a leading academic medical center dedicated to advancing healthcare through innovative clinical research and comprehensive patient care. As a prominent sponsor of clinical trials, the hospital leverages its expertise in various medical disciplines to facilitate cutting-edge studies that aim to improve treatment outcomes and enhance patient safety. With a strong commitment to collaboration, the University Hospital of Grenoble engages in partnerships with academic institutions, industry leaders, and regulatory bodies to drive scientific discovery and translate research findings into clinical practice. Its state-of-the-art facilities and multidisciplinary teams ensure rigorous adherence to ethical standards and regulatory guidelines, fostering an environment where groundbreaking research can thrive.

Locations

Grenoble, , France

Patients applied

0 patients applied

Trial Officials

Louis-Marie GALERNEAU, MD, PhD

Principal Investigator

University Hospital, Grenoble

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported