Influence of Healing Time on the Outcomes of Alveolar Ridge Preservation in Periodontally Compromised Extraction Sockets

Launched by SHANGHAI NINTH PEOPLE'S HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY · Oct 21, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how the healing time after tooth extraction affects the success of a procedure called alveolar ridge preservation. This procedure is important for patients who have lost teeth due to gum disease, as it helps prepare the jawbone for a dental implant. Researchers want to see if allowing the extraction site to heal for 3 months, instead of the usual 6 months, can still lead to good results when placing an implant.

To be eligible for this study, participants must be at least 18 years old and need a molar tooth extraction due to periodontal disease. They should have enough bone remaining around the extraction site to support the grafting material used in the procedure. If you join the study, you will first have a special 3D scan to guide the surgery. After your tooth is extracted and the graft is placed, you’ll return for follow-up visits at 2 weeks, and then at either 3 or 6 months for implant placement. Overall, this trial aims to find the best timing for healing before getting a dental implant, which could help many patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 18 years of age or older
• • ASA (American Society of Anesthesia) status I or II
• • Need for molar extraction due to periodontal disease with or without chronic endodontic involvement, complying with the presentation of periodontitis stage III/IV
• • Radiographic evidence of a bone dehiscence on at least one socket wall, where the height of the horizontal (suprabony) component of the defect (alveolar bone crest - cement-enamel junction) is \>50% of the corresponding root length as measured on CBCT scans prior to extraction (Ben Amara et al., 2021)
• • Radiographic evidence of at least 3 mm of residual bone wall height
• • Presence of at least one adjacent tooth to the extraction site
• • Treatment plan must include tooth replacement with an implant-supported fixed dental prosthesis
• Exclusion Criteria:
• • Extraction of multiple adjacent teeth
• • Acute infection associated with the tooth to be extracted or with adjacent teeth
• • Current smokers (\>10 cigarettes per day)
• • Uncontrolled diabetes mellitus (HbA1c \>7.0)
• • Any active oral or systemic acute infections
• • Currently receiving chemo- or radiotherapy or a history of radiotherapy in the head and neck area
• • Diseases or medications that may compromise normal wound healing