The PharmFIT Study

Launched by UNC LINEBERGER COMPREHENSIVE CANCER CENTER · Oct 22, 2024

Keywords

ClinConnect Summary

The PharmFIT Study is a clinical trial designed to find out if a new approach, called Pharmacy-based FIT (PharmFIT), can help increase the number of people getting screened for colorectal cancer. Colorectal cancer screening is important because it can help catch the disease early when it’s easier to treat. This study will involve about 1,200 patients who are between the ages of 45 and 75 and have not had the recommended screenings in the last few years. Participants will be randomly assigned to either receive the usual care or the PharmFIT intervention, which aims to make screening more accessible and convenient.

To be eligible for this trial, you need to be a patient at a participating primary care clinic, live in North Carolina or Washington, and be within the specified age range. You’ll also need access to the internet, as some parts of the study may involve online surveys or information. Throughout the study, researchers will assess how well the PharmFIT program works, any challenges that come up, and how much it costs to implement. This trial not only seeks to improve screening rates but also hopes to gather valuable information that could help in future healthcare efforts.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria: Clinic and pharmacy staff (n up to 100)
• • Age ≥18 years
• • Employed at a participating primary care clinic or pharmacy
• • Fluent in English
• • Has access to a computer with internet
• • Exclusion Criteria: Clinic and pharmacy staff
• • Floaters/per diem employees
• • Those who would object to having their interview audio recorded
• • Those who would object to participation in evaluation surveys
• • Inclusion Criteria: Patients (n=1400)
• • Age 45-75 years
• • Patient at a participating primary care facility (medical visit within last 18 months)
• • Current resident of NC or WA state
• • Not up to date with recommended screening (e.g., no colonoscopy within 10 years, no FIT-DNA test within 3 years; no FIT/FOBT within 12 months)
• • English and Spanish speakers
• • Has access to a computer or smartphone with internet
• • Exclusion Criteria: Patients
• • Previous USPST CRC screening within recommended screening period: 1) Colonoscopy within the past 10 years, 2) FIT/FOBT/FIT-DNA test within the past 12 months, 3) Previous sigmoidoscopy within the past 5 years, 4) Previous CT colonography within the past 10 years, 5) Other CRC screening tests
• • CRC screening is contraindicated
• • Previous positive FIT/FOBT/FIT-DNA
• • Colorectal neoplasm or colorectal polyp
• • Adenoma by biopsy
• • Family history of colorectal cancer
• • Diagnosed with inflammatory bowel disease
• • Total or partial colectomy
• • Diagnosis of Alzheimer's/other forms of severe dementia
• • Resides in an assisted living facility
• • Currently receiving hospice care
• • Diagnosed with end stage renal disease
• • Current diagnosis of certain cancers (e.g., CRC, mesothelioma, glioblastoma, lung, pancreatic, and liver/bile duct)