PDA for Kidneys Study

Launched by UNIVERSITY OF WISCONSIN, MADISON · Oct 24, 2024

Keywords

ClinConnect Summary

The PDA for Kidneys Study is looking at how a condition called patent ductus arteriosus (PDA) affects the oxygen levels in the kidneys of newborn babies. PDA is a heart issue that some babies are born with, and researchers want to learn more about how it might relate to kidney health. To do this, they will use special ultrasound images of the heart, check urine samples, and measure the oxygen levels in the kidneys. This study aims to find out more about potential kidney injury in babies with this condition.

This trial is open to babies who were born early (before 32 weeks of pregnancy) and are less than 72 hours old. They need to be staying in the neonatal intensive care unit (NICU) at Meriter Hospital, and at least one parent or guardian should be able to understand English or Spanish to provide consent. Babies with certain serious kidney problems or those whose doctors think might not survive their first days will not be eligible. If your baby participates, they will undergo non-invasive tests to help researchers gather important information about kidney health in relation to PDA.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Delivered at \<32 weeks' gestation
• • ≤72 hours of age
• • Inpatient at Meriter Hospital, Inc. NICU
• • At least one parent/guardian is able to provide parental permission in English or Spanish
• Exclusion Criteria:
• • Major congenital anomalies of kidney
• • Attending physician's discretion to not place NIRS sensors due to clinical concerns
• • In the PI or Co-I's medical opinion, there is a significant likelihood that the neonate would not survive the first 3 days of life
• • Birth parent aged \<18