Different Low Flow Rates on Gas Exchange in Children During Apnea

Launched by YASSER S MOSTAFA, MD · Oct 24, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different low flow rates of oxygen affect the buildup of carbon dioxide in children who are temporarily not breathing, a condition known as apnea, during anesthesia for surgery. The researchers want to understand how these low flow rates can help manage the levels of carbon dioxide in the body during this short period of not breathing, which lasts for about three minutes.

The trial is open to children aged 1 to 6 years who weigh between 10 and 20 kilograms and are scheduled for elective surgery under general anesthesia. To participate, children must be in good health, specifically classified as having low-risk physical status. However, children with certain health conditions, like severe asthma or sleep apnea, will not be eligible. Families who consent to participate can expect their child to receive different levels of oxygen flow while they are under anesthesia, helping doctors learn more about how to keep children safe during surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Children aged 1 to 6 years old weighting 10-20 kg.
• • American Society of Anesthesiologists (ASA) physical status I or II.
• • Children will be scheduled for elective surgery under general anesthesia.
• Exclusion Criteria:
• • Parent refusal
• • Patient required nasal intubation
• • Children with a cardio-respiratory disease like asthma or recent upper respiratory infection.
• • Anemia.
• • Obstructive sleep apnea, sepsis.
• • Children prone to hypoxia or hypercarbia, and upper airway obstruction.
• • Children reported to have nasal obstruction .