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Search / Trial NCT06660797

Irrigation Activating Techniques on Irrigant Penetration Depth and Microbial Reduction

Launched by TANTA UNIVERSITY · Oct 25, 2024

Trial Information

Current as of June 27, 2025

Recruiting

Keywords

Different Irrigation Activating Techniques Primary Endodontic Infection Cases

ClinConnect Summary

This clinical trial is investigating how different techniques for activating irrigation solutions can improve the cleaning of root canals, which are the spaces inside teeth that can become infected or damaged. The goal is to see how well these techniques help the cleaning solution penetrate deeper into the canal and reduce the amount of bacteria present. This is important for treating endodontic disease, or infections related to the tooth's root.

To participate in the study, individuals must have teeth that need root canal treatment but are not currently causing any pain. Candidates should have healthy gums and should not have any signs of infection, like pus. The study is open to both men and women aged between 18 and 80. However, people with certain health conditions, such as systemic diseases or those who are pregnant, cannot participate. If you join the trial, you can expect to undergo a standard root canal procedure with the added benefit of contributing to research that may improve future treatments for similar conditions.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • Asymptomatic vital/non vital teeth requiring root canal treatment.
  • Teeth with sound periodontal apparatus.
  • Teeth without pus or inflammatory exudates draining through the canal.
  • Teeth without anatomic variations.
  • Teeth with sinus tract.
  • Exclusion Criteria:
  • • Patients with any systemic diseases.
  • Pregnant or lactating patients.
  • Immunocompromised patients.
  • Apparently thin roots in which apical preparation with #40 or #50 file would be overzealous.
  • Patient allergic to anything used in this procedure especially rubber dam material and Iohexol (radiographic contrast media).
  • Retreatment cases. Teeth with calcified canals.

About Tanta University

Tanta University is a prestigious academic institution located in Egypt, dedicated to advancing medical research and education. As a clinical trial sponsor, Tanta University leverages its extensive resources and expertise to conduct innovative research initiatives aimed at improving health outcomes. The university collaborates with a network of healthcare professionals, researchers, and institutions to facilitate rigorous clinical trials across various medical disciplines. Committed to ethical standards and scientific integrity, Tanta University strives to contribute to the global body of knowledge while fostering the next generation of medical professionals.

Locations

Tanta, , Egypt

Patients applied

0 patients applied

Trial Officials

Ali Mahmoud Farag, Phd

Principal Investigator

Professor of Endodontics

Dalia Abd Elhameed Sherif, Phd

Study Director

Lecturer of Endodontics

Kareman Ahmed Ebrahim Eshra, Phd

Principal Investigator

Professor of clinical Microbiology and Immunology

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported