Irrigation Activating Techniques on Irrigant Penetration Depth and Microbial Reduction
Launched by TANTA UNIVERSITY · Oct 25, 2024
Trial Information
Current as of June 27, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is investigating how different techniques for activating irrigation solutions can improve the cleaning of root canals, which are the spaces inside teeth that can become infected or damaged. The goal is to see how well these techniques help the cleaning solution penetrate deeper into the canal and reduce the amount of bacteria present. This is important for treating endodontic disease, or infections related to the tooth's root.
To participate in the study, individuals must have teeth that need root canal treatment but are not currently causing any pain. Candidates should have healthy gums and should not have any signs of infection, like pus. The study is open to both men and women aged between 18 and 80. However, people with certain health conditions, such as systemic diseases or those who are pregnant, cannot participate. If you join the trial, you can expect to undergo a standard root canal procedure with the added benefit of contributing to research that may improve future treatments for similar conditions.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • • Asymptomatic vital/non vital teeth requiring root canal treatment.
- • Teeth with sound periodontal apparatus.
- • Teeth without pus or inflammatory exudates draining through the canal.
- • Teeth without anatomic variations.
- • Teeth with sinus tract.
- Exclusion Criteria:
- • • Patients with any systemic diseases.
- • Pregnant or lactating patients.
- • Immunocompromised patients.
- • Apparently thin roots in which apical preparation with #40 or #50 file would be overzealous.
- • Patient allergic to anything used in this procedure especially rubber dam material and Iohexol (radiographic contrast media).
- • Retreatment cases. Teeth with calcified canals.
About Tanta University
Tanta University is a prestigious academic institution located in Egypt, dedicated to advancing medical research and education. As a clinical trial sponsor, Tanta University leverages its extensive resources and expertise to conduct innovative research initiatives aimed at improving health outcomes. The university collaborates with a network of healthcare professionals, researchers, and institutions to facilitate rigorous clinical trials across various medical disciplines. Committed to ethical standards and scientific integrity, Tanta University strives to contribute to the global body of knowledge while fostering the next generation of medical professionals.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Tanta, , Egypt
Patients applied
Trial Officials
Ali Mahmoud Farag, Phd
Principal Investigator
Professor of Endodontics
Dalia Abd Elhameed Sherif, Phd
Study Director
Lecturer of Endodontics
Kareman Ahmed Ebrahim Eshra, Phd
Principal Investigator
Professor of clinical Microbiology and Immunology
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported