GYNecologic Cancer-Related COGnitive Impairment

Launched by NORTHWESTERN UNIVERSITY · Oct 25, 2024

Keywords

ClinConnect Summary

This clinical trial is looking to help women who have been diagnosed with gynecologic cancers, such as ovarian or cervical cancer, and have finished their chemotherapy treatment. Some of these patients experience difficulties with thinking and memory, often referred to as cognitive impairment. The study is testing a special training program that patients can do at home, designed to improve their cognitive abilities and help them feel better.

To be eligible for this trial, participants need to be women aged 18 and older who have completed chemotherapy and have reported some issues with their thinking skills. They must also speak and write in English and have internet access to take part in assessments. However, women with certain pre-existing mental health conditions or those currently involved in other cognitive training programs won’t be able to participate. If you join the study, you can expect to receive support tailored to your needs as you work on improving your cognitive skills from the comfort of your home.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Female; ≥18 years of age
• • Presents to clinic with a confirmed diagnosis of a gynecologic cancer (e.g., ovarian, endometrial, cervical, or vulvar cancer) who have completed adjuvant chemotherapy with at least stable disease at time of screening.
• • Screen positive for subjective cognitive impairment by answering affirmatively to at least one of three screener questions
• • Fluent in spoken and written English
• • Have access to the internet to complete assessments
• Exclusion Criteria:
• • Patients who have not received chemotherapy
• • Patients with pre-existing neuropsychiatric disorders that would impact cognitive function, such as dementia, Alzheimer's disease, and schizophrenia.
• • Patients with non-gynecologic causes of incurable metastatic cancers.
• • Patients undergoing active interventions in other cognitive trials or patients currently using cognitive training programs such as Brain HQ, Luminosity, Elevate, Peak, Fit Brains, or CogniFit.
• • Patients with self-report of learning disability or an unwillingness to participate in technology-based cognitive training programs.
• • Pregnant women or prisoners
• • Patients with impaired-decision making capacity