Fitness and Nutrition in Glioma

Launched by NYU LANGONE HEALTH · Oct 29, 2024

Keywords

ClinConnect Summary

The "Fitness and Nutrition in Glioma" trial is a research study looking at how a special diet and exercise can help patients with malignant glioma, a type of brain cancer. This pilot study will involve 15 participants who will follow a modified Atkins diet, which is low in carbohydrates, along with a fitness program over 15 weeks. Participants will take part in two supervised exercise sessions each week and will also have an exercise program they can do at home.

To be eligible for this study, participants need to have a confirmed diagnosis of high-grade glioma and be in good enough health to engage in moderate to vigorous physical activities. They must also be able to commit to the study and give informed consent. Unfortunately, those currently receiving radiation or chemotherapy, or who have serious health issues that prevent them from exercising or following a restrictive diet, will not be eligible. This trial offers an opportunity to explore how lifestyle changes can impact the health and well-being of patients battling this challenging condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Tissue confirmed diagnosis of high-grade glioma (World Health Organization grade III or IV)
• • Karnofsky Performance Status (KPS) ≥ 70%
• • Willing to follow the study intervention and follow-up
• • Able to give full informed consent
• Exclusion Criteria:
• • Currently undergoing initial concurrent radiation/chemotherapy
• • Severe medical co-morbidities
• • Any medical condition which prohibits moderate to vigorous physical activity (60-85% HRmax)
• • Any medical condition which prohibits a restrictive diet
• • Neurological deficit preventing participation in moderate to vigorous physical activity
• • Severe psychiatric illness