Correlation Between Acute Gastrointestinal Injury and Venous Return in Critical Ill Patients

Launched by PEKING UNION MEDICAL COLLEGE HOSPITAL · Oct 30, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating how changes in blood flow to the intestines might affect patients with acute gastrointestinal injury who are critically ill. Researchers want to understand if monitoring the return of blood from the abdomen can help detect problems in the intestines earlier, allowing for better treatment. The study is innovative because it explores a connection that hasn't been thoroughly researched before.

To be eligible for this trial, participants must be between 18 and 80 years old, have sepsis (a severe infection) with an expected stay in the Intensive Care Unit (ICU) of more than three days, and meet certain health criteria. If you join the study, you can expect to undergo some additional monitoring to assess your intestinal blood flow. The goal is to improve how we recognize and treat intestinal issues in critically ill patients, which could lead to better outcomes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients with sepsis with an expected ICU stay of more than 3 days.
• • 2. ≥18 years of age and \<80 years of age.
• Exclusion Criteria:
• • 1. Severe mesenteric or abdominal artery stenosis;
• • 2. Fixed body (such as recent spinal surgery or intracranial hypertension);
• • 3. Patients with contraindications for IAP measurement (such as patients who have recently undergone bladder surgery, been injured, or become pregnant）
• • 4. Having undergone abdominal surgery or chest lowering involving the intestines patients undergoing aortic surgery;
• • 5. Poor quality of abdominal ultrasound images;
• • 6. Hydrothorax or ascites.