Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer Techniques to Improve Facial Function and Quality of Life
Launched by M.D. ANDERSON CANCER CENTER · Oct 29, 2024
Trial Information
Current as of August 21, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how certain surgeries, specifically nerve transfer techniques, can help improve facial function and quality of life for patients with facial paralysis caused by head and neck cancer. The researchers want to see if these surgeries can make a positive difference for patients who have had issues with their facial nerves due to cancer treatments.
To be eligible for this study, participants must be at least 18 years old and scheduled for a facial nerve transfer surgery. They need to understand the study and agree to follow all procedures. There is also a group for individuals who have previously had surgery that damaged their facial nerve but did not receive a reconstruction. Patients who are pregnant cannot participate. Those who join the study can expect to share their experiences and any changes in their quality of life after the surgery, helping researchers gather important information about these treatments.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- In order to be eligible to participate in the intervention group of this study, an individual must meet all of the following criteria:
- • Provision of signed and dated informed consent form
- • Aged 18 or greater
- • Patient scheduled to undergo facial nerve transfer
- • Stated willingness to comply with all study procedures and lifestyle considerations and availability for the duration of the study
- In order to be eligible to participate in the non-intervention historical control group of this study, an individual must meet all of the following criteria:
- • Provision of signed and dated informed consent form
- • Aged 18 or greater
- • Previous facial surgery severing a facial nerve without graft or other form of dynamic facial nerve reconstruction within the last 5 years
- Exclusion Criteria:
- • Patients known to be pregnant
About M.D. Anderson Cancer Center
The University of Texas MD Anderson Cancer Center is a leading institution dedicated to cancer care, research, education, and prevention. As one of the world’s most respected cancer centers, MD Anderson focuses on innovative treatment approaches and groundbreaking clinical trials aimed at improving patient outcomes. With a multidisciplinary team of experts and state-of-the-art facilities, the center is committed to advancing cancer research and providing comprehensive, personalized care to patients. MD Anderson's clinical trials play a pivotal role in translating scientific discoveries into effective therapies, positioning the center at the forefront of cancer treatment and research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Houston, Texas, United States
Patients applied
Trial Officials
Z-Hye Lee, MD
Principal Investigator
M.D. Anderson Cancer Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported