multipaRameter mOnitoring systeM for sedAtion iNThe ICu

Launched by PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE · Oct 30, 2024

Keywords

ClinConnect Summary

This clinical trial, called ROMANTIC, is studying a new system designed to monitor sedation levels in patients who are critically ill and in Intensive Care Units (ICUs). Proper sedation is crucial for these patients, as both too little and too much sedation can lead to serious complications, such as longer recovery times and even increased risk of death. The goal of the trial is to develop an advanced monitoring system that uses machine learning to provide more accurate and continuous assessments of sedation levels. This could help healthcare providers give the right amount of sedation more quickly, potentially reducing complications like delirium and the time patients spend on mechanical ventilation.

To be eligible for this trial, participants must be adults over 18 who are admitted to an ICU and require sedation and mechanical ventilation for more than 24 hours. Certain conditions, like pregnancy or specific neurological issues, may exclude individuals from participating. If you or a loved one qualify for this trial, you can expect to be part of a study that aims to improve how sedation is managed, potentially leading to better outcomes and shorter ICU stays for critically ill patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients admitted to adult critical care units
• • Individuals over 18 years old
• • Requiring sedation for more than 24 hours
• • Patients needing mechanical ventilation for more than 24 hours
• Exclusion Criteria:
• • Patients with neurological pathology as the cause of mechanical ventilation (including recovered cardiocirculatory arrest, fulminant liver failure, and neurocritical conditions, except subdural hematomas or subarachnoid hemorrhages).
• • Pregnancy
• • Presence of psychiatric or intellectual disability prior to hospitalization
• • Drug dependency
• • History of chronic liver damage with hepatic encephalopathy
• • Second period of mechanical ventilation during hospitalization
• • Early limitation of therapeutic effort
• • Patients under 18 years old