Does Co-administration of Lactate Affect Postprandial Nutrient Absorption and Fat Disposition?

Launched by UNIVERSITY OF AARHUS · Oct 30, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating whether taking lactate with meals can improve how the body absorbs nutrients and manages fat in people with pre-diabetes. The researchers believe that adding lactate might help reduce fat storage and improve the way the body handles fats after eating. This study is currently recruiting participants who are 50 years or older, have a specific range of blood sugar levels (known as HbA1c), and can give their consent to participate.

Eligible participants will be asked to take lactate with their meals and then will be monitored to see how their bodies respond. It's important to note that individuals who are taking certain medications that affect blood sugar or have recently changed their medications may not be eligible for this study. Participants should also be able to speak and understand Danish. This trial offers a chance to explore a new approach to managing pre-diabetes and may provide insights that could benefit others in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 50+ years
• • Written and oral consent
• • HbA1c 39-47 mmol/L
• Exclusion Criteria:
• • Medicine with an impact on blood glucose and glucose metabolism.
• • Newly started medicine (\<3 months prior to the inclusion time)
• • Medicine changes (\<3 months prior to the inclusion time and planned changes during the trial)
• • Affected screening blood sample as evaluated by PI
• • Hba1c \> 47
• • Allergy to paracetamol
• • Doesn't speak or understand Danish
• • Special diets
• • The eight healthy individuals will be included by the same criteria except for not having pre-diabetes