Quantitative Eye Movement Measurements in Patients with Acute Vestibular Syndrome

Launched by ALEXANDER TARNUTZER · Oct 30, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how eye movements and pupil responses can help doctors better understand the causes of acute vestibular syndrome (AVS), which includes conditions like severe dizziness and vertigo. The goal is to find reliable tests that can quickly distinguish between more serious causes, like a stroke, and less serious ones. This is important because about 25% of patients with AVS have a stroke that is often missed during initial evaluations. By using special equipment and tests, the researchers hope to improve the accuracy of diagnoses for patients experiencing sudden dizziness.

To participate in the trial, individuals must be at least 18 years old and have experienced dizziness for 5 days or less, with the ability to undergo an MRI (a type of brain scan). Participants will undergo various eye movement tests and assessments to help researchers understand their condition better. This trial is not yet recruiting participants, but it aims to enhance how emergency departments evaluate and treat patients with dizziness, potentially leading to better outcomes and fewer misdiagnoses.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient groups
• • patients presenting with an AVS (peripheral or central), with symptom duration of 5 days or less
• • being able to receive brain MRI
• * All groups:
• • Being able to give informed consent as documented by signature
• • Age 18 years or above
• Exclusion Criteria:
• • Aged less than 18 years.
• • Pregnant or lactating women
• • Inability or contraindications to undergo the investigated intervention (including brain MRI in the patient groups),
• • Clinically significant concomitant diseases such neurodegenerative disorders (e.g. Alzheimer's disease, Parkinson's disease)
• • Pre-existing peripheral-vestibular / central-vestibular deficits
• • History of brainstem / cerebellar stroke
• • Pre-existing or acute severe visual loss
• • Pre-existing severe hearing loss.
• • Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, aphasia.