Diagnosis of Respiratory Disorders by the Numerical Modeling.

Launched by UNIVERSITY HOSPITAL, BORDEAUX · Oct 30, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating a new way to understand and diagnose chronic nasal obstruction (CNO) using advanced computer models that simulate how air flows through the nasal passages. Currently, doctors rely on patients’ self-reported questionnaires about their symptoms, which can be influenced by many factors, making it hard to measure their condition accurately. By using these numerical models, the study aims to provide a clearer picture of how airflow affects breathing comfort in both healthy individuals and those suffering from nasal obstruction.

To participate in this trial, you should be between 18 and 70 years old, have a body mass index (BMI) under 30, and be of Caucasian or Mediterranean descent. You could either be healthy with a slight nasal deviation or have more significant nasal problems that might need surgery. Participants will undergo assessments to help researchers gather data on airflow in their nasal passages. It's important to note that certain conditions, like chronic sinusitis or previous nasal surgeries, may exclude you from participating. This study hopes to improve the way chronic nasal obstruction is diagnosed and managed, ultimately leading to better health outcomes for patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 18 years ≤ age \< 70 years
• • BMI \< 30 kg/m2
• • Subject or Patient of Caucasian ethnic origin or from the Mediterranean region.
• • Asymptomatic subject with or without a septal deviation without sinonasal disease with a NOSE score ≤ 7 Or Patient suffering from chronic nasal obstruction of morphological origin (symptomatic septal or nasoseptal deviation) requiring surgical management with a NOSE score ≥ 9/20, without or .with sleep apnea with an Apnea-hypopnea index ≤ 20 with no other cause than this apnea syndrome
• Exclusion Criteria:
• • Acute or chronic rhinosinusitis with or without polyps (except controlled allergic rhinitis)
• • Vasculitis
• • Empty nasal cavity syndrome
• • Septal perforations
• • History of nasal plastic surgery, sinonasal endoscopic surgery and cancer with head or neck radiotherapy
• • Uncontrolled bronchopulmonary pathology
• • Treatments with nasal vasomotor repercussions.