Post-Operative Antibiotic Efficacy in Clean Contaminated Head and Neck Surgery: A Randomized Controlled Trial
Launched by SHAUKAT KHANUM MEMORIAL CANCER HOSPITAL & RESEARCH CENTRE · Nov 1, 2024
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
In the pre-antibiotic era, surgery was a perilous endeavour, fraught with high infection risks and grim patient outcomes. Surgeons waged a relentless battle against postoperative infections. Even routine procedures were laden with danger, leading to severe complications, high morbidity, and alarming mortality rates. The inability to curb bacterial growth in surgical wounds cast a dark shadow over the medical field, highlighting the desperate need for a revolutionary breakthrough in infection control.
The Discovery of Penicillin in 1928 by Sir Alexander Fleming marked the beginning of the A...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Patients aged 18 years and older.
- • 2. Patients undergoing elective Clean-contaminated head and neck surgery.
- • 3. Patients who have provided informed consent.
- • 4. Patients with a life expectancy of more than 6 months.
- Exclusion Criteria:
- • 1. Patients aged less than 18.
- • 2. Patients with a history of antibiotic allergies.
- • 3. Patients with ongoing infections or those requiring preoperative antibiotics.
- • 4. Patients with immunocompromised conditions (e.g., HIV, on immunosuppressive therapy).
- • 5. Patients undergoing emergency surgery.
- • 6. Patients undergoing palliative surgery.
- • 7. Patients undergoing Clean Head and Neck Surgery.
About Shaukat Khanum Memorial Cancer Hospital & Research Centre
Shaukat Khanum Memorial Cancer Hospital & Research Centre (SKMCH&RC) is a leading institution in Pakistan dedicated to the treatment and research of cancer. Established in memory of the renowned philanthropist and cricket legend Imran Khan's mother, the hospital provides state-of-the-art cancer care and conducts innovative clinical trials aimed at advancing cancer treatment and improving patient outcomes. With a commitment to excellence in healthcare, SKMCH&RC integrates clinical research with patient care, fostering an environment of discovery and collaboration among healthcare professionals and researchers. The institution is recognized for its contributions to oncological research and its efforts to make cancer care accessible to all, regardless of financial status.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Lahore, Punjab, Pakistan
Patients applied
Trial Officials
Dr. Syed Raza Hussain Consultant Oro-Maxillo-Facial Surgeon, MBBS, BDS, FDSRCS (ENG,IRL)
Study Chair
Shaukat Khanum Memorial Cancer Hospital and Research Centre
Dr. Muhammad Faisal Consultant Head & Neck Surgery, BDS,FCPS,FHNS
Study Chair
Shaukat Khanum Memorial Cancer Hospital and Research Centre
Dr. Shayan Khalid Ghaloo Senior Instructor Head & Neck Surg., MBBS,FCPS
Study Director
Shaukat Khanum Memorial Cancer Hospital and Research Centre
Dr. Muhammad Awais Kanwal, MBBS,B.Sc
Principal Investigator
Shaukat Khanum Memorial Cancer Hospital and Research Centre
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported