Changes in Pulse-Oximetry Perfusion Index Induced by Tidal Volume Challenge Versus Fluid Volume Challenge to Detect Preload Responsiveness in Mechanically Ventilated Patients With Low Tidal Volume
Launched by BENHA UNIVERSITY · Nov 2, 2024
Trial Information
Current as of September 10, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
No description provided
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients of both genders aged 18 years or older Invasive mechanical ventilation in assist controlled mode with a Vt of 6 mL/kg PBW, Patients with circulatory failure Decision by the clinicians in charge to assess preload responsiveness through a Vt Challenge and a Fluid Challenge test.
- • Patients in sinus rhythm
- Exclusion Criteria:
- • Open chest Pulmonary hypertension Poor lung compliance (Crs \<30 ml/cmH2O) Obesity (BMI≥35) Pregnancy Intraabdominal hypertension Prone position Atrial fibrillation
About Benha University
Benha University, a leading institution in Egypt, is dedicated to advancing medical research and innovation through rigorous clinical trials. With a strong emphasis on multidisciplinary collaboration, the university aims to enhance healthcare outcomes by exploring novel therapeutic approaches and interventions. Its state-of-the-art facilities and commitment to ethical research practices ensure that all trials are conducted with the highest standards of integrity and scientific rigor. Benha University actively contributes to the global medical community by fostering partnerships and disseminating findings that can improve patient care and inform public health policies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Banhā, Al Qalyubia, Egypt
Patients applied
Trial Officials
Ahmed Mostafa Abdelhamid
Principal Investigator
Benha University
Samar Rafik Mohamed Amin
Principal Investigator
Benha University
Mona Sobhy Emara
Principal Investigator
Benha University
Salwa Abbas Awad Eltahawy
Principal Investigator
Benha University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported