ClinConnect ClinConnect Logo
Search / Trial NCT06674824

Role of Spectrophotometer in Early Prediction of Weaning Induced Cardiac Dysfunction

Launched by AIN SHAMS UNIVERSITY · Nov 4, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Massimo

ClinConnect Summary

This clinical trial is studying a new method to help doctors determine when critically ill patients can safely stop using a breathing machine. Many patients struggle to breathe on their own after being on a ventilator, and this can lead to what is known as weaning failure. The trial is testing a tool called the plethysmography variability index (PVI), which is a simple and non-invasive way to measure how well a patient's body can handle fluids. By using PVI, doctors hope to predict whether a patient will successfully breathe on their own during a trial period without the ventilator.

To participate in this trial, patients need to be between the ages of 65 and 74 and currently receiving intubation and mechanical ventilation, with certain criteria met for moving towards extubation (removing the breathing tube). However, patients with unstable heart conditions or those who have had a tracheostomy (a different method of breathing support) will not be eligible. If patients qualify and choose to join, they can expect to undergo assessments using the PVI tool as part of their care, which could help improve their chances of successfully transitioning off the ventilator.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Intubation and mechanical ventilation
  • 2. Fulfilling criteria for extubation
  • 3. Fraction inspired oxygen less than 50%
  • Exclusion Criteria:
  • a. Hemodynamic instability b. b. tracheostomy

About Ain Shams University

Ain Shams University, established in Cairo, Egypt, is a prestigious higher education institution renowned for its commitment to academic excellence and research innovation. As a clinical trial sponsor, the university leverages its extensive resources and expertise in various medical and scientific disciplines to advance healthcare through rigorous research initiatives. With a focus on ethical practices and adherence to regulatory standards, Ain Shams University aims to contribute to the development of new therapies and improve patient outcomes, fostering collaboration among researchers, healthcare professionals, and industry partners in the pursuit of medical advancements.

Locations

Cairo, , Egypt

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported