The Optimal Injection Site for a 3D Guided Inferior Alveolar Nerve Block Device (IANBD)
Launched by BOSTON UNIVERSITY · Nov 4, 2024
Trial Information
Current as of July 09, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial, titled "The Optimal Injection Site for a 3D Guided Inferior Alveolar Nerve Block Device (IANBD)," is exploring a new way to provide anesthesia for dental procedures involving the lower jaw. Traditional methods of numbing this area can be tricky and may not always work well, leading to discomfort for patients. This trial will test a new device that uses 3D imaging to precisely guide the injection of anesthesia, aiming to improve the success rate on the first try and reduce pain and tissue damage.
To participate in this trial, individuals must be patients at Boston University’s dental school and need non-surgical endodontic therapy (a common dental procedure) on specific teeth in the lower jaw. They should be generally healthy and have certain dental conditions that allow for treatment. Participants can expect to receive anesthesia through this new guided method, and the trial will help researchers learn about its safety and effectiveness. It's important to note that not everyone can join; for example, individuals with allergies to specific medications or those who are pregnant won't be eligible.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patient of Henry M. Goldman School of Dentistry (GSDM)
- • Medical History indicating American Society of Anesthesiology (ASA)1
- • Need Non-surgical Endodontic Therapy on Mandibular Molar or Premolar
- • Asymptomatic pulpal diagnosis (normal, necrotic, asymptomatic irreversible pulpitis, retreatment with no symptoms)
- • The quadrant to be treated must have at least 3 vital teeth.
- • Going to receive a CBCT required for clinical purposes
- • Must be willing to receive guided IANB
- Exclusion Criteria:
- • Allergy to lidocaine or articaine
- • Resin allergy
- • Normal teeth unresponsive to thermal testing (ie calcified chamber)
- • Prior jaw surgery
- • Currently pregnant
About Boston University
Boston University, a leading research institution located in Boston, Massachusetts, is dedicated to advancing health sciences through innovative clinical trials and research initiatives. With a strong emphasis on interdisciplinary collaboration, the university leverages its extensive network of experts and state-of-the-art facilities to conduct rigorous clinical studies aimed at improving patient outcomes and addressing pressing health challenges. Boston University is committed to ethical research practices, patient safety, and the dissemination of findings to foster greater understanding and advancements in medical care.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Tum-Yi Hsu, DMD DScD
Principal Investigator
BU Goldman School of Dental Medicine, Endodontics
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported