Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle
Launched by MISR UNIVERSITY FOR SCIENCE AND TECHNOLOGY · Nov 4, 2024
Trial Information
Current as of July 04, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking to find out how effective different treatments are for relieving pain in the jaw muscles, specifically the masseter muscle, which is often affected by a condition called myofascial pain. The study will compare injections of Botox, magnesium sulfate, and a saline solution (a harmless saltwater solution) in patients aged 16 to 50 who have had trigger points (painful spots) in their jaw muscles for at least six months. Researchers want to learn which treatment lasts the longest, has the fewest side effects, and most improves patients' quality of life.
To participate, individuals must have a confirmed diagnosis of myofascial pain and trigger points in the jaw, and they should not have had any prior invasive treatments in the same area. Participants will need to visit the clinic four times: the first visit for their treatment, and then follow-ups at one month, three months, and six months to track their progress. This trial is not yet recruiting, so interested individuals will need to wait for it to start.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients diagnosed with orofacial pain and trigger points in the masseter muscle unilaterally or bilaterally for at least period 6 months other criteria
- • Definite diagnosis of myofascial pain based on the DC/TMD criteria with a referral
- • Presence of one or more unilateral or bilateral trigger points in the masseter muscle
- • No history of any invasive procedures of the related masseter muscle (Taşkesen, Cezairli, 2023.)
- Exclusion Criteria:
- • Any painful conditions (other than myofascial trigger points) affecting the orofacial region
- • Any systemic diseases that could affect masticatory function (e.g., rheumatoid arthritis and epilepsy
- • Pregnancy and lactation. (Refahee, Mahrous, Shabaan,2022)
About Misr University For Science And Technology
MISR University for Science and Technology is a leading institution dedicated to advancing healthcare and scientific research through innovative clinical trials. With a strong focus on interdisciplinary collaboration, the university leverages its diverse expertise to address pressing medical challenges and enhance patient outcomes. Committed to ethical research practices and regulatory compliance, MISR University fosters a robust environment for clinical investigation, aiming to contribute valuable insights to the global medical community. Through its rigorous methodologies and emphasis on scientific excellence, the university strives to translate research findings into tangible health solutions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Giza, , Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported