Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Launched by ASTRAZENECA · Nov 5, 2024
Trial Information
Current as of June 27, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the effects of a medication called Baxdrostat combined with Dapagliflozin on heart failure and cardiovascular death in adults aged 40 and older who have type 2 diabetes and existing heart and blood vessel diseases. The trial aims to see if this combination can help improve heart health and reduce serious health events, like hospitalizations for heart failure or cardiovascular death. Participants will go through some initial screenings to see if they qualify, and those who do will take Dapagliflozin for a few weeks before being randomly assigned to receive either the study medication or a placebo.
To be eligible for this trial, participants need to be at least 40 years old, diagnosed with type 2 diabetes, and have a history of high blood pressure and cardiovascular disease. They should also have a certain level of potassium in their blood and at least one additional risk factor for heart failure, such as being older than 70 or having kidney problems. Throughout the study, participants will have regular check-ins at the clinic to monitor their health, and even if the study medication needs to be stopped for any reason, they will continue to receive the Dapagliflozin. This trial is currently recruiting and aims to gather important information to help improve treatment options for heart failure.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Participants of any sex and gender must be ≥ 40 years old at the time of signing the informed consent.
- • 2. Diagnosed with T2DM and requiring treatment
- • 3. Established CV disease (ischaemic heart disease, cerebrovascular disease, peripheral arterial disease)
- • 4. History of HTN and an SBP ≥ 130 mmHg at screening and ≥ 120 mmHg at the Randomisation Visit.
- • 5. Central laboratory serum potassium must meet the following criteria at the Screening
- Visit, based on screening eGFR:
- • for participants with screening eGFR ≥ 45 mL/min/1.73 m2, potassium must be
- • ≥ 3.0 and ≤ 4.8 mmol/L at the Screening Visit
- • for participants with screening eGFR \< 45 mL/min/1.73 m2, potassium must be ≥ 3.0 and ≤ 4.5 mmol/L at the Screening Visit
- 6. At least one additional risk factor for HF:
- • Age ≥ 70 years
- • UACR \> 20 mg/g
- • eGFR \< 60 mL/min/1.73 m2
- • History of polyvascular disease (at least two of: ischaemic heart disease, cerebrovascular disease, and peripheral arterial disease)
- • History of atrial fibrillation or atrial flutter
- • NT-proBNP \> 125 ng/L
- Exclusion Criteria:
- • 1. Previously confirmed diagnosis and treatment of heart failure
- • 2. An eGFR \< 30 mL/min/1.73 m2 at screening
- • 3. Known hyperkalaemia, defined as potassium ≥ 5.5 mmol/L within 3 months prior to screening
- • 4. Type 1 diabetes mellitus or uncontrolled T2DM with HbA1c \> 10.5% (\> 91 mmol/mol) at screening
- • 5. Serum sodium \< 135 mmol/L at screening, determined as per central laboratory assessment
- • 6. Stroke, transient ischaemic cerebral attack, valve implantation or valve replacement, carotid surgery, carotid angioplasty, or cardiac surgery, within 3 months prior to randomisation
- • 7. Myocardial infarction within 3 months prior to randomisation, or within 1 month prior to randomisation when there is no further planned revascularisation
- • 8. Percutaneous coronary intervention within 1 month prior to randomisation
- • 9. Known severe hepatic impairment, defined as Child-Pugh Class C, based on records that confirm documented medical history
- • 10. Documented history of adrenal insufficiency
- • 11. Any dialysis (including for acute kidney injury) within 3 months prior to screening
- • 12. Any acute kidney injury within 3 months prior to screening
- • 13. History or known allergy/hypersensitivity to the study treatment, as judged by the Investigator (eg, SGLT2i or active substance or excipients)
- • 14. History of organ transplant or bone marrow transplant, or planned organ transplant within 6 months following randomisation (including kidney transplant)
- • 15. Any clinical condition requiring systemic immunosuppression therapy other than maintenance therapy (stable for at least 3 months prior to screening)
- • 16. Drug or alcohol abuse that in the Investigator's judgement makes the participant a poor candidate for the study
- • 17. Any use of mineralocorticoid receptor antagonists (such as spironolactone, eplerenone, or finerenone) or aldosterone synthase inhibitor within 4 weeks prior to screening and/or during the study
- • 18. Concomitant therapy with strong inducers of cytochrome P450
- • 19. Use of potassium-sparing diuretics (such as triamterene or amiloride) and direct renin inhibitor (eg, aliskiren) at the time of screening
- • 20. Use of potassium binders (such as sodium zirconium cyclosilicate, patiromer, or sodium polystyrene sulfonate) within 4 weeks prior to screening
About Astrazeneca
AstraZeneca is a global biopharmaceutical company dedicated to the discovery, development, and commercialization of innovative medicines across various therapeutic areas, including oncology, cardiovascular, respiratory, and autoimmune diseases. With a strong commitment to scientific research and patient-centric solutions, AstraZeneca leverages cutting-edge technology and a robust pipeline to address unmet medical needs. The company collaborates with healthcare professionals, academic institutions, and other organizations to advance clinical trials and deliver transformative therapies, aiming to improve health outcomes and enhance the quality of life for patients worldwide.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Porto Alegre, , Brazil
Katowice, , Poland
Lublin, , Poland
Szczecin, , Poland
Warszawa, , Poland
Englewood, Colorado, United States
Nashville, Tennessee, United States
Bydgoszcz, , Poland
Indianapolis, Indiana, United States
Greenville, South Carolina, United States
Shumen, , Bulgaria
Crystal River, Florida, United States
Nyíregyháza, , Hungary
Székesfehérvár, , Hungary
A Coruña, , Spain
Madrid, , Spain
Krakow, , Poland
Medford, Oregon, United States
Missoula, Montana, United States
Omaha, Nebraska, United States
San Diego, California, United States
Woodstock, Georgia, United States
Waterbury, Connecticut, United States
Cincinnati, Ohio, United States
São Paulo, , Brazil
Berlin, , Germany
Huntington Beach, California, United States
Caen, , France
Jerusalem, , Israel
Napoli, , Italy
Siena, , Italy
Nijmegen, , Netherlands
Lund, , Sweden
Wolverhampton, , United Kingdom
Budapest, , Hungary
Plovdiv, , Bulgaria
Varna, , Bulgaria
Barcelona, , Spain
Dundee, , United Kingdom
Torino, , Italy
Lenexa, Kansas, United States
Raleigh, North Carolina, United States
Esbjerg, , Denmark
Marseille, , France
Athens, , Greece
Bari, , Italy
Rotterdam, , Netherlands
Málaga, , Spain
Istanbul, , Turkey
Debrecen, , Hungary
Gdańsk, , Poland
Birmingham, Alabama, United States
Mobile, Alabama, United States
Columbia, Missouri, United States
New Bern, North Carolina, United States
Beaumont, Texas, United States
Richmond, Virginia, United States
Haskovo, , Bulgaria
Pleven, , Bulgaria
St. John's, Newfoundland And Labrador, Canada
Sherbrooke, Quebec, Canada
Benesov, , Czechia
Frederiksberg, , Denmark
Herlev, , Denmark
Hvidovre, , Denmark
Roskilde, , Denmark
Svendborg, , Denmark
Bochum, , Germany
Heidelberg, , Germany
Leipzig, , Germany
Kalocsa, , Hungary
Szolnok, , Hungary
Tel Aviv, , Israel
Pavia, , Italy
Udine, , Italy
Deventer, , Netherlands
Haarlem, , Netherlands
Zabrze, , Poland
Targu Mures, , Romania
Lucenec, , Slovakia
Uppsala, , Sweden
Novara, , Italy
Orbassano, , Italy
Aguascalientes, , Mexico
Angers, , France
Le Coudray, , France
Bamberg, , Germany
Freiburg, , Germany
Görlitz, , Germany
Kaiserslautern, , Germany
Kassel, , Germany
Ludwigshafen, , Germany
Neuruppin, , Germany
Weinheim, , Germany
Thessaloniki, , Greece
Foggia, , Italy
Milano, , Italy
Sugar Land, Texas, United States
La Roche Sur Yon Cedex 9, , France
Brescia, , Italy
Troy, Michigan, United States
Norman, Oklahoma, United States
Ramat Gan, , Israel
Tel Aviv, , Israel
Laval, Quebec, Canada
Atlanta, Georgia, United States
Culiacán, , Mexico
San Juan Del Rio, , Mexico
Quezon City, , Philippines
Halifax, Nova Scotia, Canada
Chiang Mai, , Thailand
Valencia, , Spain
Adelaide, , Australia
Uzhhorod, , Ukraine
Hialeah, Florida, United States
Mount Pleasant, South Carolina, United States
Geelong, , Australia
Amiens, , France
Durban, , South Africa
Salem, Virginia, United States
Fort Myers, Florida, United States
Fort Lauderdale, Florida, United States
Paducah, Kentucky, United States
Saint Louis, Missouri, United States
El Paso, Texas, United States
Beijing, , China
Chania, , Greece
Larissa, , Greece
Tainan, , Taiwan
Rozzano, , Italy
Roma, , Italy
Sofia, , Bulgaria
Brooklyn, New York, United States
Aachen, , Germany
South Bend, Indiana, United States
Portsmouth, New Hampshire, United States
Rimavska Sobota, , Slovakia
Viborg, , Denmark
Bratislava, , Slovakia
Namestovo, , Slovakia
Swansea, , United Kingdom
Munster, Indiana, United States
Nantes Cedex 1, , France
Pierre Benite, , France
Grants Pass, Oregon, United States
Cona, , Italy
Besançon Cedex, , France
Kanazawa Shi, , Japan
Thousand Oaks, California, United States
Norfolk, Nebraska, United States
Suwon Si, , Korea, Republic Of
Iloilo City, , Philippines
Lipa City, , Philippines
Taipei, , Taiwan
Bangkok, , Thailand
Ubonratchathani, , Thailand
Sydney, Nova Scotia, Canada
Herning, , Denmark
Durango, , Mexico
Venlo, , Netherlands
Amsterdam, , Netherlands
Roy, Utah, United States
Burke, Virginia, United States
Charlottesville, Virginia, United States
Toulouse Cedex 9, , France
Jacksonville, Florida, United States
Buenos Aires, , Argentina
Caba, , Argentina
Elizabeth Vale, , Australia
Milton, , Australia
Cambridge, Ontario, Canada
Guelph, Ontario, Canada
Siping, , China
Suzhou, , China
Yinchuan, , China
Bad Oeynhausen, , Germany
Balatonfüred, , Hungary
Szigetvár, , Hungary
Kota Samarahan, , Malaysia
Kuching, , Malaysia
Sungai Buloh, , Malaysia
Guadalajara, , Mexico
Hoogeveen, , Netherlands
Cebu, , Philippines
Kosice, , Slovakia
Roznava, , Slovakia
Centurion, , South Africa
Lenasia, , South Africa
Paarl, , South Africa
Somerset West, , South Africa
Umkomaas, , South Africa
Changhua, , Taiwan
Kaohsiung, , Taiwan
Deggingen, , Germany
Wangen, , Germany
Paris Cedex 15, , France
Potenza, , Italy
Montreal, Quebec, Canada
Aalborg, , Denmark
Essen, , Germany
Inglewood, California, United States
San Francisco, California, United States
Langen, , Germany
George, , South Africa
London, , United Kingdom
Columbus, Georgia, United States
Baltimore, Maryland, United States
Izmir, , Turkey
Ioannina, , Greece
Alessandria, , Italy
Lund, , Sweden
Sarnia, Ontario, Canada
Brno, , Czechia
Craiova, , Romania
Roosendaal, , Netherlands
Praha 2, , Czechia
Berlin, , Germany
Albuquerque, New Mexico, United States
Changchun, , China
Xi'an, , China
Veracruz, , Mexico
Seongnam Si, , Korea, Republic Of
Katowice, , Poland
Mölndal, , Sweden
Ostrava, , Czechia
New Bedford, Massachusetts, United States
San Dimas, California, United States
Canton, Georgia, United States
Piraeus, , Greece
Villeurbanne, , France
Bergamo, , Italy
Monza, , Italy
Toruń, , Poland
Clermont Ferrand, , France
Montpellier Cedex 5, , France
Miami, Florida, United States
Beltsville, Maryland, United States
Mar Del Plata, , Argentina
San Nicolás, , Argentina
Santa Fe, , Argentina
Maroubra, , Australia
Wollongong, , Australia
São Paulo, , Brazil
Calgary, Alberta, Canada
Toronto, Ontario, Canada
Montréal, Quebec, Canada
Saint Charles Borromee, Quebec, Canada
Regina, Saskatchewan, Canada
Quebec, , Canada
Quebec, , Canada
Changsha, , China
Hodonin, , Czechia
Le Creusot, , France
Gyöngyös, , Hungary
Cheongju Si, , Korea, Republic Of
Seoul, , Korea, Republic Of
Acapulco, , Mexico
Culiacan, , Mexico
Monterey, , Mexico
Ede, , Netherlands
Chrzanów, , Poland
Krakow, , Poland
Lublin, , Poland
Wrocław, , Poland
Iasi, , Romania
Košice, , Slovakia
Prievidza, , Slovakia
Diepkloof, Soweto, , South Africa
Worcester, , South Africa
Sant Joan Despi, , Spain
Kyiv, , Ukraine
Vinnytsia, , Ukraine
Ho Chi Minh City, , Vietnam
Falls Church, Virginia, United States
Mar Del Plata, , Argentina
Rosario, , Argentina
Hamburg, , Germany
Bucheon Si, , Korea, Republic Of
Gdynia, , Poland
Ostrów Mazowiecka, , Poland
Tarnów, , Poland
Hospitalet De Llobregat(barcel, , Spain
Malatya, , Turkey
Ivano Frankivsk, , Ukraine
Aberdeen, , United Kingdom
Ho Chi Minh, , Vietnam
Suwanee, Georgia, United States
Charlotte, North Carolina, United States
Brandys Nad Labem, , Czechia
Aarhus N, , Denmark
Lyon, , France
Olsztyn, , Poland
Helsingborg, , Sweden
Sivas, , Turkey
Chesterfield, , United Kingdom
Sandbach, , United Kingdom
Amberg, , Germany
Hillerød, , Denmark
Shenyang, , China
Saint Augustine, Florida, United States
Palermo, , Italy
Sherwood Park, Alberta, Canada
Taoyuan, , Taiwan
Homburg, , Germany
Lincoln, California, United States
Loma Linda, California, United States
Palmetto Bay, Florida, United States
Monroe, North Carolina, United States
Fairhope, Alabama, United States
Merewether, , Australia
Jinan, , China
Pingxiang, , China
Hjørring, , Denmark
Bobigny, , France
Markkleeberg, , Germany
Papenburg, , Germany
Pécs, , Hungary
Bangalore, , India
Petah Tikva, , Israel
Matsudo Shi, , Japan
Toyota Shi, , Japan
Daegu, , Korea, Republic Of
Wonju Si, , Korea, Republic Of
Enschede, , Netherlands
Lima, , Peru
Chojnice, , Poland
Jasło, , Poland
Myszków, , Poland
Rzeszów, , Poland
Cape Town, , South Africa
Santiago(a Coruña), , Spain
Hsinchu, , Taiwan
Taichung, , Taiwan
Hat Yai, , Thailand
Naimuang, , Thailand
Adana, , Turkey
Antalya, , Turkey
Hcmc, , Vietnam
Gainesville, Florida, United States
Paris, , France
Glasgow, , United Kingdom
Mankato, Minnesota, United States
Guangzhou, , China
Petrich, , Bulgaria
Sendai Shi, , Japan
Fremantle, , Australia
Mirabel, Quebec, Canada
Békéscsaba, , Hungary
Hakusan Shi, , Japan
Meguro Ku, , Japan
Tsuchiura Shi, , Japan
Beek, , Netherlands
Piaseczno, , Poland
Pretoria, , South Africa
Taipei City, , Taiwan
Hanoi, , Vietnam
Lakewood, California, United States
Austin, Texas, United States
Frankfurt, , Germany
Izumo Shi, , Japan
Ueda Shi, , Japan
Shanghai, , China
Hai Phong, , Vietnam
Khon Kaen, , Thailand
Krnov, , Czechia
Ha Noi, , Vietnam
Porto Alegre, , Brazil
Vijayawada, , India
Xalapa, , Mexico
Bellavista, , Peru
New Taipei, , Taiwan
Hue, , Vietnam
Aurillac Cedex, , France
Haifa, , Israel
Szeged, , Hungary
Oldenburg, , Germany
Ternopil, , Ukraine
Pearland, Texas, United States
Parow, , South Africa
Aarhus, , Denmark
Tel Aviv, , Israel
Kuantan, , Malaysia
St. John, New Brunswick, Canada
Praha 10, , Czechia
Praha 4, , Czechia
Nanchang, , China
Wenzhou, , China
Helsingborg, , Sweden
Uwajima Shi, , Japan
Baotou, , China
Linhai, , China
Bad Homburg, , Germany
Gelnhausen, , Germany
Hamburg, , Germany
Münster, , Germany
Pirna, , Germany
Nanjing, , China
Itabashi Ku, , Japan
Ogaki Shi, , Japan
Göteborg, , Sweden
Cordoba, , Spain
Córdoba, , Argentina
Gurgaon, , India
Benoni, , South Africa
Olomouc, , Czechia
Rome, , Italy
Brooklyn, Maryland, United States
Davao City, , Philippines
Orosháza, , Hungary
Montreal, Quebec, Canada
Haßloch, , Germany
Eskisehir, , Turkey
Warszawa, , Poland
Mesquite, Texas, United States
Wuhan, , China
Hengyang, , China
Campinas, , Brazil
Moncton, New Brunswick, Canada
Newmarket, Ontario, Canada
North York, Ontario, Canada
Oakville, Ontario, Canada
Chifeng, , China
Xuzhou, , China
Belagavi, , India
Karamsad, , India
Azumino Shi, , Japan
Mito Shi, , Japan
Amagasaki Shi, , Japan
Kamakura Shi, , Japan
Osaka Shi, , Japan
Cuernavaca, , Mexico
Chorrillos, , Peru
Panagyurishte, , Bulgaria
Hengelo, , Netherlands
Lishui, , China
Brasilia, , Brazil
Johor Bahru, , Malaysia
Seri Manjung, , Malaysia
Chengdu, , China
Vigo, , Spain
Spearwood, , Australia
Nantong, , China
Corbeil Essonnes Cedex, , France
Khlong Luang, , Thailand
Durham, North Carolina, United States
Taiyuan, , China
Rio De Janeiro, , Brazil
Yokohama Shi, , Japan
Lakeland, Florida, United States
Beavercreek, Ohio, United States
Asahikawa Shi, , Japan
Częstochowa, , Poland
Cordoba, , Argentina
Tianjin, , China
Jaromer, , Czechia
Groningen, , Netherlands
Naunhof, , Germany
Kingswood, , Australia
Szczecin, , Poland
Harderwijk, , Netherlands
Rockhampton, , Australia
Chongqing, , China
Sao Paulo, , Brazil
Vandoeuvre Les Nancy Cedex, , France
København, , Denmark
Kaifeng, , China
Changzhou, , China
Beer Sheba, , Israel
Satu Mare, , Romania
Göteborg, , Sweden
Sao Jose Do Rio Preto, , Brazil
San Vicente, , Argentina
Cholet, , France
La Rochelle, , France
Yangsan Si, , Korea, Republic Of
Belem, , Brazil
Osaka, , Japan
Malacca, , Malaysia
Biała Podlaska, , Poland
Muang, , Thailand
Ottawa, Ontario, Canada
Norrköping, , Sweden
Nagano, , Japan
Brezno, , Slovakia
Oita Shi, , Japan
Piura, , Peru
Las Pinas, , Philippines
Chicago, Illinois, United States
Milan, , Italy
Miyazaki Shi, , Japan
Bydgoszcz, , Poland
Munich, , Germany
Bragança Paulista, , Brazil
Skórzewo, , Poland
Hengyang, , China
Zapopan, , Mexico
Dusit, , Thailand
Natal, , Brazil
Trois Rivières, Quebec, Canada
Broumov, , Czechia
Kishiwada Shi, , Japan
Kütahya, , Turkey
New Delhi, , India
Sanya, , China
Kahramanmaras, , Turkey
Ajmer, , India
Changde, , China
Reinfeld (Holstein), , Germany
Angeles City, , Philippines
Terrebonne, Quebec, Canada
Sapporo Shi, , Japan
Roxas City, , Philippines
Malacky, , Slovakia
Elsterwerda, , Germany
Ahmedabad, , India
Puerto Princesa City, , Philippines
Sarawak Miri, , Malaysia
Hualien City, , Taiwan
Nanyang, , China
Linyi, , China
Panjin, , China
Potsdam, , Germany
Paris, Texas, United States
Bucharest, , Romania
Kolkata, , India
łódź, , Poland
North Charleston, South Carolina, United States
Surat, , India
Svidník, , Slovakia
Campina Grande Do Sul, , Brazil
Linhai, , China
Midrand, , South Africa
Holbæk, , Denmark
Yate, , United Kingdom
Liaocheng, , China
Zigong, , China
Abbotsford, British Columbia, Canada
Potomac, Maryland, United States
Manadaluyong City, , Philippines
Stockholm, , Sweden
Kyoto Shi, , Japan
Police Nad Metují, , Czechia
Völklingen, , Germany
Chiavari, , Italy
Afyonkarahisar, , Turkey
Huizhou, , China
Płock, , Poland
Massapequa, New York, United States
Morristown, Tennessee, United States
Abilene, Texas, United States
Wallerfing, , Germany
Alor Setar, , Malaysia
Brest Cedex, , France
Wichita, Kansas, United States
Juiz De Fora, , Brazil
Heze, , China
Horsham, Pennsylvania, United States
Bechhofen, , Germany
Himeji, , Japan
Białystok, , Poland
Piekary śląskie, , Poland
Samsun, , Turkey
Luoyang, , China
Meihekou, , China
Xianyang, , China
Sao Jose Dos Campos, , Brazil
Yanagawa Shi, , Japan
San Nicolas De Los Arroyos, , Argentina
Leipzig, , Germany
Markham, Ontario, Canada
Delhi, , India
Hyderabad, , India
Nagpur, , India
Nyíregyháza Sóstóhegy, , Hungary
Yokkaichi Shi, , Japan
Ankara, , Turkey
Sevilla, , Spain
Weston Super Mare, , United Kingdom
Bois Guillaume, , France
Chernivtsі, , Ukraine
Plzeň, , Czechia
Banphaeo, , Thailand
Roslindale, Massachusetts, United States
Woodway, Texas, United States
Hamilton, Ontario, Canada
Harbin, , China
Vestavia Hills, Alabama, United States
Zhytomyr, , Ukraine
Itabashi, , Japan
Poznań, , Poland
Dresden, , Germany
Fulda, , Germany
Köln, , Germany
Nittendorf, , Germany
Fuente Osmena Cebu City, , Philippines
Bansuan, Muang, Chonburi, , Thailand
Jining, , China
Rawang, , Malaysia
Friedrichsthal, , Germany
Obertshausen, , Germany
Zwenkau, , Germany
Lucknow, , India
La Plata, , Argentina
Taichung City, , Taiwan
Blumenau, , Brazil
Curitiba, , Brazil
Tatuí, , Brazil
Russe, , Bulgaria
Joliette, Quebec, Canada
Levis, Quebec, Canada
Huangshi, , China
Zhumadian, , China
Chlumec Nad Cidlinou, , Czechia
Humpolec, , Czechia
Jílové U Prahy, , Czechia
Prague, , Czechia
Praha, , Czechia
Dijon, , France
Holon, , Israel
Mondovi, , Italy
Aizu Wakamatsu Shi, , Japan
Kakegawa Shi, , Japan
Kita Ku, , Japan
Takamatsu Shi, , Japan
Ciudad De México, , Mexico
Cuauhtemoc, , Mexico
Santiago De Querétaro, , Mexico
Amsterdam, , Netherlands
Den Bosch, , Netherlands
Zwolle, , Netherlands
Bacau, , Romania
Baia Mare, , Romania
Brasov, , Romania
Bucuresti, , Romania
Ploiesti, , Romania
Sabinov, , Slovakia
ľubochňa, , Slovakia
Brackenfell, , South Africa
East London, , South Africa
Kocaeli, , Turkey
Heol Maes Eglwys, , United Kingdom
Norwich, , United Kingdom
Penzance, , United Kingdom
Redruth, , United Kingdom
Southampton, , United Kingdom
Woodbridge, , United Kingdom
Vinh Yen, , Vietnam
Glendale, California, United States
Surrey, British Columbia, Canada
Centreville, Alabama, United States
Kawaguchi Shi, , Japan
Kraków, , Poland
Dublin, California, United States
El Dorado, Kansas, United States
Caba, , Argentina
Gistrup, , Denmark
Slagelse, , Denmark
Colombes, , France
Narbonne Cedex, , France
Bremen, , Germany
Osnabrück, , Germany
Herzelia, , Israel
Saitama Shi, , Japan
Shizuoka Shi, , Japan
Gatley, , United Kingdom
Stockton On Tees, , United Kingdom
Olsztyn, , Poland
Leabrook, , Australia
Mulgrave, , Australia
Osborne Park, , Australia
Przemyśl, , Poland
Radzionków, , Poland
Huddinge, , Sweden
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported