NeuroCatch Reference Interval Database

Launched by HEALTHTECH CONNEX INC. · Nov 5, 2024

Keywords

ClinConnect Summary

The NeuroCatch Reference Interval Database study is looking to understand how the brain responds to sounds and words. This research aims to collect data that compares brain responses from different individuals, helping us see how these responses might vary based on age and gender. The study will involve around 810 healthy participants who will undergo a brain scan using a device called NeuroCatch® Platform 2, which has been approved for use in Canada. The study is taking place at the Centre for Neurology Studies in Surrey, BC, and potentially at other nearby locations.

To join the study, participants need to be at least 6 years old, be able to focus and sit still for about 7 minutes, and be in good health without any significant history of brain-related illnesses or injuries. It’s important that participants can understand the study and its requirements, and if they are under 19, a parent or guardian will need to give consent. Those with certain conditions, like hearing issues, neurological disorders, or severe medical problems affecting brain function, would not be eligible to participate. If you decide to take part, you'll be contributing to valuable research that could help improve our understanding of brain function across different people.

Gender

ALL

Eligibility criteria

• • INCLUSION CRITERIA
• • 1. Any sex, at least 6 years of age or older
• • 2. Able to understand the informed consent/assent form (in English), study procedures and willing to participate in study; participants under 19 must also have a parent/guardian who is able to understand and provide informed consent on their behalf.
• • 3. Able to remain seated and focused for 7 minutes
• • 4. In good health with no history of clinically relevant neurological illness or injury
• • EXCLUSION CRITERIA
• • 1. Requires the use of hearing aids or a cochlear implant, diagnosed with tinnitus that is currently active, or has temporary damage to hearing (e.g., punctured ear drum). Or unable to detect a 740Hz tone played at 85dB in both ears.
• • 2. Implanted pacemaker or other electrical stimulator(s)
• • 3. Metal or plastic implants in the skull, excluding dental/facial implants.
• • 4. Not native-level in English
• • 5. Previous exposure to the NeuroCatch® Platform 2 audio sequences in the last 3 months
• • 6. History of clinically relevant neurological disorders or injury (e.g., epilepsy, Parkinson's disease, traumatic brain injury, etc.)
• • 7. History of chronic pain or chronic headache disorders (e.g. migraine, tension headaches, fibromyalgia, etc.)
• • 8. Currently diagnosed with any sleeping disorders (e.g. sleep apnea, hypersomnia, insomnia, parasomnia, etc.)
• • 9. Diagnosed with any memory disorders.
• • 10. History of clinically relevant major psychiatric disorders (e.g., schizophrenia, bipolar disorder, etc.)
• • 11. History of alcohol or substance misuse that, in the opinion of the Investigator, may impact brain function
• • 12. Use of medications that affect brain function (e.g., antiepileptic drugs, antipsychotics, stimulants, etc.)
• • 13. Serious medical conditions affecting brain functions (e.g., stroke, brain tumor, neurodegenerative diseases, etc.)
• • 14. Undergoing chemotherapy or any form of intensive long-term therapy that, in the opinion of the Investigator, may impact brain function.
• • 15. Unhealthy scalp (e.g., apparent open wounds and/or bruised or weakened skin)
• • 16. Allergy to EEG gel