Effect of Adding Magnesium Sulphate As Adjuvant to Bupivacaine in Ultrasound Guided External Oblique Intercostal Plane Block in Upper Abdominal Cancer Surgery.to Assess the Total Postoperative Opioid Consumption in the First 24 H and Evaluate Post Operative VAS Score

Launched by ASSIUT UNIVERSITY · Nov 5, 2024

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ClinConnect Summary

This clinical trial is studying whether adding magnesium sulfate to a common pain medication called bupivacaine can help reduce the amount of opioids needed after upper abdominal cancer surgery. The trial will use a special ultrasound technique to deliver the medications to help manage pain more effectively. Researchers want to see if this combination can lower the total opioid consumption in the first 24 hours after surgery and improve patients' pain scores.

To be eligible for this trial, participants need to be at least 18 years old and in good enough health based on a specific scoring system used by anesthesiologists. This means they should be able to have regional anesthesia safely. However, individuals who refuse to participate, have allergies to the study medications, or have certain medical conditions like severe infections or heart issues will not be included. If you join the trial, you will receive either the magnesium sulfate and bupivacaine or just the bupivacaine, and neither you nor the doctors will know which one you receive until the study is complete. This helps ensure the results are fair and unbiased.

Gender

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Eligibility criteria

• Inclusion Criteria:
• • a. Age \>18 years old b. Both sex c. Patients who were in risk-scoring groups I-III of the American Society of Anesthesiologists (ASA)
• Exclusion Criteria:
• • c. Patients' refusal, d. History of allergy to any of the study medications e. Any contraindications to regional anesthesia. f. Patients with anatomical abnormalities. g. Patients have hemodynamic instability. h. Patients with local infection, and suspected intra-abdominal sepsis.