Characteristic Transcriptomic, Proteomic and Metabolomic Molecular Studies of Nasal Secretions From Chronic Rhinitis

Launched by THE FIRST AFFILIATED HOSPITAL WITH NANJING MEDICAL UNIVERSITY · Nov 6, 2024

Keywords

ClinConnect Summary

This clinical trial is studying chronic rhinitis, a condition that causes inflammation in the nasal passages and leads to symptoms like a stuffy or runny nose, sneezing, and itching. The researchers want to better understand the different types of chronic rhinitis by analyzing samples from patients' nasal secretions. The goal is to develop a simple and effective way to diagnose the various subtypes of chronic rhinitis, which can help doctors provide better treatment options for patients.

To participate in the trial, you need to be between 18 and 65 years old and have a diagnosis of chronic rhinitis. You must be willing to provide nasal samples to help with the research. However, if you have recently taken certain medications, have serious health issues, smoke, are pregnant or breastfeeding, or have had nasal surgery in the past five months, you may not be eligible to join. If you qualify and choose to participate, you will contribute to important research that could improve how chronic rhinitis is diagnosed and treated in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age 18-65 years old;
• • 2. Patients with chronic rhinitis in the Department of Otorhinolaryngology, the First Affiliated Hospital of Nanjing Medical University;
• • 3. Patients who are willing to provide specimens for free to promote the diagnosis of chronic rhinitis.
• Exclusion Criteria:
• • 1. Patients received glucocorticoids, immunomodulatory drugs, antihistamines, and other treatments that may affect the study results within the past 1 month.
• • 2. Patients with unstable diseases (including severe asthma) and active immune system diseases;
• • 3. Smoking;
• • 4. Pregnant or lactating women; History of nasal surgery within 5.3 months;
• • 6. Patients with low compliance and refusing to accept specimen and questionnaire collection