Deep Neuromuscular Blockade on Postoperative Pain

Launched by SEOUL NATIONAL UNIVERSITY HOSPITAL · Nov 6, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different levels of muscle relaxation, known as neuromuscular blockade, affect pain after surgery in young children. Specifically, it focuses on children aged 2 months to under 7 years who are scheduled to have laparoscopic surgery, which is a type of minimally invasive surgery done with small incisions. The goal is to understand how varying degrees of muscle relaxation during surgery might change the amount of pain these children feel afterward.

To be eligible for this study, children must be in good health, classified as ASA Physical Status I, II, or III, meaning they have no major health issues. However, children who are having emergency surgery, have chronic pain, or have certain medical conditions, such as heart problems or muscle disorders, cannot participate. If chosen to take part in the trial, families can expect close monitoring and care during and after the surgery, with the aim of improving pain management for pediatric patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Pediatric patients aged over 2 months to under 7 years scheduled for laparoscopic surgery under general anesthesia.
• • American Society of Anesthesiologists (ASA) Physical Status Classification I, II, or III.
• Exclusion Criteria:
• • Patients undergoing emergency surgery.
• • Patients with chronic pain or currently taking analgesics for chronic pain.
• • Known hypersensitivity to general anesthetic agents or analgesics.
• • Patients with underlying cardiovascular disease.
• • Patients with neuromuscular disorders.
• • Any other condition that, in the investigator's judgment, would make the patient unsuitable for participation in the study.