Early Ascitis Parencentesis in SBP

Launched by CENTRE HOSPITALIER UNIVERSITAIRE DE BESANCON · Nov 6, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the timing of a procedure called paracentesis in patients with a liver condition known as cirrhosis who develop an infection in the fluid that builds up in their abdomen, called spontaneous bacterial peritonitis (SBP). The researchers want to see if doing the paracentesis earlier, at 24 hours instead of the usual 48 hours, can help doctors start the right antibiotic treatment sooner, which could lead to better health outcomes for patients.

To be eligible for this trial, participants must be at least 18 years old, have cirrhosis, and have a specific type of infection in their abdominal fluid. They also need to be part of the French social security system and provide their consent to participate. Participants can expect to undergo the paracentesis procedure as part of their care, and by joining the study, they may help improve treatment options for future patients with similar conditions. It's important to note that individuals who are pregnant, under legal protection, or have had recent surgery may not be able to participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Men and women aged 18 or over
• • Affiliation with a French social security
• • Signature of the informed consent form
• • Cirrhosis
• • Ascites fluid infection with PNN \> 250/mm3
• Exclusion Criteria:
• • Pregnant women
• • Persons deprived of their liberty by judicial or administrative decision; persons under psychiatric care.
• • Adults under legal protection
• • Subjects within the exclusion period of another study
• • Other cause of abdominal infection than SBP
• • Intra-abdominal surgery \< 4 weeks